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• W1986907664 abstract "Abstract Identification of human leukocyte antigen (HLA) antigens that are known as the highest polymorphic genes has become a valuable tool for tissue transplantation, platelet transfusion, disease susceptibility or resistance, and forensic and anthropological studies. In the present study, the allele and haplotype frequencies of HLA‐A, HLA‐B, and HLA‐DRB1 were studied in 237 unrelated healthy Western Javanese (Indonesia) by the high‐resolution polymerase chain reaction‐Luminex method. A total of 18 A, 40 B, and 20 DRB1 alleles were identified. The most frequent HLA‐A, ‐B, and ‐DRB1 alleles were HLA‐A*2407 (21.6%), HLA‐B*1502 (11.6%) and HLA‐B*1513 (11.2%), and DRB1*1202 (37.8%), respectively. The most frequent two‐locus haplotypes were HLA‐A*2407‐B*3505 (7%) and HLA‐B*1513‐DRB1*1202 (9.2%), and three‐locus haplotypes were HLA‐A*3401‐B*1521‐DRB1*150201 (4.6%), HLA‐A*2407‐B*3505‐DRB1*1202 (4.3%), and HLA‐A*330301‐B*440302‐DRB1*070101 (4.2%). HLA allele and haplotype frequencies in addition to phylogenetic tree and principal component analyses based on the four‐digit sequence‐level allele frequencies for HLA‐A, HLA‐B, and HLA‐DRB1 showed that Western Javanese (Indonesia) was closest to Southeast Asian populations." @default.
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• W1986907664 date "2008-12-23" @default.
• W1986907664 modified "2023-10-16" @default.
• W1986907664 title "Polymorphisms of HLA genes in Western Javanese (Indonesia): close affinities to Southeast Asian populations" @default.
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• W1986907664 doi "https://doi.org/10.1111/j.1399-0039.2008.01178.x" @default.
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