Matches in SemOpenAlex for { <https://semopenalex.org/work/W1986932022> ?p ?o ?g. }
- W1986932022 endingPage "48" @default.
- W1986932022 startingPage "37" @default.
- W1986932022 abstract "The presence, distribution and smooth muscle motor effects of galanin and pituitary adenylate cyclase activating peptide (PACAP) were studied in the nerves of the vaginal part of the oviduct of egg-laying hens. Galanin and PACAP immunoreactivity were found both in neuronal perikarya and nerve fibres within the wall of the vaginal segment. Both populations showed a similar distribution pattern. Particularly the circular muscle and the intramural vascular net were richly innervated. A few galanin- and PACAP-IR nerve fibres extended up to the mucosal folds. Multiple labelling showed galanin to be colocalised with PACAP as well as with vasoactive intestinal polypeptide (VIP) and nitric oxide synthase (NOS) in a large, partly intrinsic neuronal subpopulation innervating the smooth muscle wall. Pharmacological in vitro experiments showed that isolated vaginal muscle strips had a spontaneous basal activity that was not affected by the neuronal conductance blocker tetrodotoxin (TTX). Galanin induced concentration-dependent contractions that were TTX-insensitive. PACAP, VIP, nitric oxide (NO) and the NO donor nitroglycerin caused concentration-dependent relaxations that were TTX-insensitive. Electrical field stimulation of isolated muscle strips induced frequency-dependent relaxations that were blocked by TTX and reduced by the NOS blocker L-nitroarginine. These data provide evidence that the vaginal part of the oviduct contains a largely intrinsic, neuronal subpopulation, capable of releasing multiple non-adrenergic, non-cholinergic (NANC) motor agents for the control of local muscular activities. In addition, we provided pharmacological evidence that VIP, NO and PACAP exert an inhibitory and galanin an excitatory action on isolated muscle strips of the vaginal part of the chicken oviduct. Our results suggest that these NANC neurotransmitters play an important role in the regulation of neuromuscular activity in this region." @default.
- W1986932022 created "2016-06-24" @default.
- W1986932022 creator A5004021022 @default.
- W1986932022 creator A5011913278 @default.
- W1986932022 creator A5022246757 @default.
- W1986932022 creator A5025756894 @default.
- W1986932022 creator A5027129747 @default.
- W1986932022 creator A5041656258 @default.
- W1986932022 creator A5043500725 @default.
- W1986932022 creator A5053409080 @default.
- W1986932022 creator A5085832818 @default.
- W1986932022 date "2004-05-01" @default.
- W1986932022 modified "2023-10-16" @default.
- W1986932022 title "Coexistence of non-adrenergic non-cholinergic inhibitory and excitatory neurotransmitters in a large neuronal subpopulation in the vaginal segment of the chicken oviduct" @default.
- W1986932022 cites W1964454007 @default.
- W1986932022 cites W1965578455 @default.
- W1986932022 cites W1966882363 @default.
- W1986932022 cites W1968513661 @default.
- W1986932022 cites W1968908922 @default.
- W1986932022 cites W1978833748 @default.
- W1986932022 cites W1979484646 @default.
- W1986932022 cites W1981423842 @default.
- W1986932022 cites W1986071903 @default.
- W1986932022 cites W1992399074 @default.
- W1986932022 cites W1995616752 @default.
- W1986932022 cites W2009195858 @default.
- W1986932022 cites W2011285612 @default.
- W1986932022 cites W2014035772 @default.
- W1986932022 cites W2018500202 @default.
- W1986932022 cites W2018924233 @default.
- W1986932022 cites W2021255147 @default.
- W1986932022 cites W2021613066 @default.
- W1986932022 cites W2025666771 @default.
- W1986932022 cites W2026784668 @default.
- W1986932022 cites W2030194062 @default.
- W1986932022 cites W2030195234 @default.
- W1986932022 cites W2030815991 @default.
- W1986932022 cites W2032259372 @default.
- W1986932022 cites W2034503782 @default.
- W1986932022 cites W2035898712 @default.
- W1986932022 cites W2037371170 @default.
- W1986932022 cites W2049380439 @default.
- W1986932022 cites W2050762878 @default.
- W1986932022 cites W2050780404 @default.
- W1986932022 cites W2053167415 @default.
- W1986932022 cites W2053419443 @default.
- W1986932022 cites W2058104052 @default.
- W1986932022 cites W2065873596 @default.
- W1986932022 cites W2066318568 @default.
- W1986932022 cites W2069126397 @default.
- W1986932022 cites W2071723398 @default.
- W1986932022 cites W2081035140 @default.
- W1986932022 cites W2085647938 @default.
- W1986932022 cites W2086669245 @default.
- W1986932022 cites W2086962416 @default.
- W1986932022 cites W2089304706 @default.
- W1986932022 cites W2090579218 @default.
- W1986932022 cites W2090699569 @default.
- W1986932022 cites W2094788949 @default.
- W1986932022 cites W2112341182 @default.
- W1986932022 cites W2149053800 @default.
- W1986932022 cites W2164902296 @default.
- W1986932022 cites W2904717823 @default.
- W1986932022 cites W4255359567 @default.
- W1986932022 doi "https://doi.org/10.1016/j.autneu.2004.04.002" @default.
- W1986932022 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15233929" @default.
- W1986932022 hasPublicationYear "2004" @default.
- W1986932022 type Work @default.
- W1986932022 sameAs 1986932022 @default.
- W1986932022 citedByCount "8" @default.
- W1986932022 countsByYear W19869320222013 @default.
- W1986932022 countsByYear W19869320222017 @default.
- W1986932022 countsByYear W19869320222023 @default.
- W1986932022 crossrefType "journal-article" @default.
- W1986932022 hasAuthorship W1986932022A5004021022 @default.
- W1986932022 hasAuthorship W1986932022A5011913278 @default.
- W1986932022 hasAuthorship W1986932022A5022246757 @default.
- W1986932022 hasAuthorship W1986932022A5025756894 @default.
- W1986932022 hasAuthorship W1986932022A5027129747 @default.
- W1986932022 hasAuthorship W1986932022A5041656258 @default.
- W1986932022 hasAuthorship W1986932022A5043500725 @default.
- W1986932022 hasAuthorship W1986932022A5053409080 @default.
- W1986932022 hasAuthorship W1986932022A5085832818 @default.
- W1986932022 hasConcept C112592302 @default.
- W1986932022 hasConcept C118303440 @default.
- W1986932022 hasConcept C126322002 @default.
- W1986932022 hasConcept C134018914 @default.
- W1986932022 hasConcept C158453852 @default.
- W1986932022 hasConcept C170493617 @default.
- W1986932022 hasConcept C17077164 @default.
- W1986932022 hasConcept C185592680 @default.
- W1986932022 hasConcept C19519825 @default.
- W1986932022 hasConcept C22885893 @default.
- W1986932022 hasConcept C2775910092 @default.
- W1986932022 hasConcept C2776741303 @default.
- W1986932022 hasConcept C2777129507 @default.
- W1986932022 hasConcept C71924100 @default.
- W1986932022 hasConcept C8330315 @default.