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- W1987028305 abstract "The acidic fraction of bakers' yeast mannan containing mannose (93.6%), nitrogen (1.0%), and phosphorus (0.6%), designated as WAM025, showed a marked antitumor activity against the ascites forms of Ehrlich, sarcoma 180 and Meth A tumors in vivo. Namely, a 100% survival of mice transplanted with Ehrlich or sarcoma 180 ascites tumor, 1×105 cells/ddY strain mouse, was obtained by the intraperitoneal administration of WAM025, 150 mg/kg/d for 10 d. This effect evoked by WAM025 seems to be attributed to the activation of peritoneal adherent cells in mice, because a significant elevation of lysosomal enzyme level and active oxygen generation was observed on the peritoneal adherent cells obtained from the mannan-administered mice." @default.
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- W1987028305 date "1983-01-01" @default.
- W1987028305 modified "2023-10-15" @default.
- W1987028305 title "Antitumor activity of acidic mannan fraction from bakers' yeast." @default.
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- W1987028305 doi "https://doi.org/10.1248/bpb1978.6.668" @default.
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