FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987032010> ?p ?o ?g. }

• W1987032010 endingPage "1184" @default.
• W1987032010 startingPage "1184" @default.
• W1987032010 abstract "A nanomechanical transducer is developed to detect and screen endocrine disrupting chemicals (EDCs) combining fluidic sample injection and delivery with bioreceptor protein functionalized microcantilevers (MCs). The adverse affects of EDCs on the endocrine system of humans, livestock, and wildlife provides strong motivation for advances in analytical detection and monitoring techniques. The combination of protein receptors, which include estrogen receptor alpha (ER-alpha) and estrogen receptor beta (ER-beta), as well as monoclonal antibodies (Ab), with MC systems employing modified nanostructured surfaces provides for excellent nanomechanical response sensitivity and the inherent selectivity of biospecific receptor-EDC interactions. The observed ranking of binding interaction of the tested EDCs with ER-beta is diethylstilbestrol (DES) > 17-beta-estradiol > 17-alpha-estradiol > 2-OH-estrone > bisphenol A > p,p'-dichlorodiphenyldichloroethylene (p,p'-DDE) with measurements exhibiting intra-day RSDs of about 3%. A comparison of responses of three EDCs, which include 17-beta-estradiol, 17-alpha-estradiol, and 2-OH-estrone, with ER-beta and ER-alpha illustrates which estrogen receptor subtype provides the greatest sensitivity. Antibodies specific to a particular EDC can also be used for analyte specific screening. Calibration plots for a MC functionalized with anti-17-beta-estradiol Ab show responses in the range of 1 x 10(-11) through 1 x 10(-7) M for 17-beta-estradiol with a linear portion extending over two orders of magnitude in concentration." @default.
• W1987032010 created "2016-06-24" @default.
• W1987032010 creator A5002299887 @default.
• W1987032010 creator A5064437440 @default.
• W1987032010 creator A5081461206 @default.
• W1987032010 creator A5083364299 @default.
• W1987032010 date "2007-01-01" @default.
• W1987032010 modified "2023-10-14" @default.
• W1987032010 title "Development of a nanomechanical biosensor for analysis of endocrine disrupting chemicals" @default.
• W1987032010 cites W1875933026 @default.
• W1987032010 cites W1974383036 @default.
• W1987032010 cites W1979297065 @default.
• W1987032010 cites W1979823631 @default.
• W1987032010 cites W1985241460 @default.
• W1987032010 cites W1989303411 @default.
• W1987032010 cites W1994151002 @default.
• W1987032010 cites W2000578237 @default.
• W1987032010 cites W2013503818 @default.
• W1987032010 cites W2030552522 @default.
• W1987032010 cites W2031471218 @default.
• W1987032010 cites W2049970571 @default.
• W1987032010 cites W2051796825 @default.
• W1987032010 cites W2061751890 @default.
• W1987032010 cites W2066874036 @default.
• W1987032010 cites W2072261888 @default.
• W1987032010 cites W2076075536 @default.
• W1987032010 cites W2086327234 @default.
• W1987032010 cites W2089135572 @default.
• W1987032010 cites W2091723149 @default.
• W1987032010 cites W2094918673 @default.
• W1987032010 cites W2100538151 @default.
• W1987032010 cites W2111714831 @default.
• W1987032010 cites W2115987142 @default.
• W1987032010 cites W2147478280 @default.
• W1987032010 cites W2153560666 @default.
• W1987032010 doi "https://doi.org/10.1039/b704723a" @default.
• W1987032010 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17713618" @default.
• W1987032010 hasPublicationYear "2007" @default.
• W1987032010 type Work @default.
• W1987032010 sameAs 1987032010 @default.
• W1987032010 citedByCount "15" @default.
• W1987032010 countsByYear W19870320102012 @default.
• W1987032010 countsByYear W19870320102017 @default.
• W1987032010 countsByYear W19870320102019 @default.
• W1987032010 countsByYear W19870320102020 @default.
• W1987032010 countsByYear W19870320102021 @default.
• W1987032010 crossrefType "journal-article" @default.
• W1987032010 hasAuthorship W1987032010A5002299887 @default.
• W1987032010 hasAuthorship W1987032010A5064437440 @default.
• W1987032010 hasAuthorship W1987032010A5081461206 @default.
• W1987032010 hasAuthorship W1987032010A5083364299 @default.
• W1987032010 hasConcept C10390740 @default.
• W1987032010 hasConcept C121608353 @default.
• W1987032010 hasConcept C126322002 @default.
• W1987032010 hasConcept C134018914 @default.
• W1987032010 hasConcept C159110408 @default.
• W1987032010 hasConcept C159654299 @default.
• W1987032010 hasConcept C160756335 @default.
• W1987032010 hasConcept C170493617 @default.
• W1987032010 hasConcept C172313692 @default.
• W1987032010 hasConcept C185592680 @default.
• W1987032010 hasConcept C203014093 @default.
• W1987032010 hasConcept C2775944032 @default.
• W1987032010 hasConcept C2777164284 @default.
• W1987032010 hasConcept C2778656385 @default.
• W1987032010 hasConcept C2780420688 @default.
• W1987032010 hasConcept C2780862370 @default.
• W1987032010 hasConcept C43617362 @default.
• W1987032010 hasConcept C46699223 @default.
• W1987032010 hasConcept C49453240 @default.
• W1987032010 hasConcept C530470458 @default.
• W1987032010 hasConcept C55493867 @default.
• W1987032010 hasConcept C64943373 @default.
• W1987032010 hasConcept C71315377 @default.
• W1987032010 hasConcept C71924100 @default.
• W1987032010 hasConcept C84606932 @default.
• W1987032010 hasConcept C86803240 @default.
• W1987032010 hasConcept C96307122 @default.
• W1987032010 hasConceptScore W1987032010C10390740 @default.
• W1987032010 hasConceptScore W1987032010C121608353 @default.
• W1987032010 hasConceptScore W1987032010C126322002 @default.
• W1987032010 hasConceptScore W1987032010C134018914 @default.
• W1987032010 hasConceptScore W1987032010C159110408 @default.
• W1987032010 hasConceptScore W1987032010C159654299 @default.
• W1987032010 hasConceptScore W1987032010C160756335 @default.
• W1987032010 hasConceptScore W1987032010C170493617 @default.
• W1987032010 hasConceptScore W1987032010C172313692 @default.
• W1987032010 hasConceptScore W1987032010C185592680 @default.
• W1987032010 hasConceptScore W1987032010C203014093 @default.
• W1987032010 hasConceptScore W1987032010C2775944032 @default.
• W1987032010 hasConceptScore W1987032010C2777164284 @default.
• W1987032010 hasConceptScore W1987032010C2778656385 @default.
• W1987032010 hasConceptScore W1987032010C2780420688 @default.
• W1987032010 hasConceptScore W1987032010C2780862370 @default.
• W1987032010 hasConceptScore W1987032010C43617362 @default.
• W1987032010 hasConceptScore W1987032010C46699223 @default.
• W1987032010 hasConceptScore W1987032010C49453240 @default.
• W1987032010 hasConceptScore W1987032010C530470458 @default.

• next