Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987060400> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1987060400 endingPage "643" @default.
- W1987060400 startingPage "638" @default.
- W1987060400 abstract "We recently reported two cases of reversible Epstein-Barr virus (EBV)—associated lymphomas in patients undergoing methotrexate therapy for rheumatic disease. The current study was undertaken to investigate how frequently lymphoid neoplasms in patients with rheumatic disease show features of lymphoproliferations occurring in immunocompromised patients. Eighteen patients (including the two previously reported patients) with rheumatoid arthritis or dermatomyositis who developed lymphoproliferative lesions and on whom detailed clinical information was available were studied. As a group these patients developed a spectrum of lymphoproliferative lesions; however, a subset of patients developed neoplasms with features associated with immunosuppression. The neoplasms occurred in extranodal sites in 10 (56%) patients, showed a diffuse large-cell histology in nine (50%) patients, and contained EBV (EBER1) transcripts and EBV latent membrane protein in six (33%) patients. In three (17%) patients the neoplasms showed the entire constellation of features typical of immunosuppression-associated lymphoproliferations, including extranodal location, large-cell or polymorphous histology, geographic areas of necrosis, and the presence of EBV. These three patients were receiving both steroids and methotrexate at the time they developed their neoplasms. The findings of this study support the hypothesis that a subset of lymphoid neoplasms in rheumatic patients occurs in an immunocompromised setting and suggest that therapeutic immunosuppression may contribute, at least in part, to the development of these lymphoid neoplasms." @default.
- W1987060400 created "2016-06-24" @default.
- W1987060400 creator A5012160968 @default.
- W1987060400 creator A5023734653 @default.
- W1987060400 creator A5024852195 @default.
- W1987060400 creator A5041872479 @default.
- W1987060400 creator A5044316474 @default.
- W1987060400 creator A5058922646 @default.
- W1987060400 date "1994-07-01" @default.
- W1987060400 modified "2023-09-28" @default.
- W1987060400 title "Lymphoid neoplasms in patients with rheumatoid arthritis and dermatomyositis: Frequency of Epstein-Barr virus and other features associated with immunosuppression" @default.
- W1987060400 cites W1834694398 @default.
- W1987060400 cites W1968885061 @default.
- W1987060400 cites W1986819764 @default.
- W1987060400 cites W2001549134 @default.
- W1987060400 cites W2005097349 @default.
- W1987060400 cites W2016704705 @default.
- W1987060400 cites W2019979528 @default.
- W1987060400 cites W2028998365 @default.
- W1987060400 cites W2053225831 @default.
- W1987060400 cites W2060438574 @default.
- W1987060400 cites W2091235787 @default.
- W1987060400 cites W2091648050 @default.
- W1987060400 cites W2114139304 @default.
- W1987060400 cites W2131658103 @default.
- W1987060400 cites W2318643269 @default.
- W1987060400 cites W2320839025 @default.
- W1987060400 cites W2321602362 @default.
- W1987060400 cites W2331320446 @default.
- W1987060400 cites W2410302560 @default.
- W1987060400 doi "https://doi.org/10.1016/0046-8177(94)90295-x" @default.
- W1987060400 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8026822" @default.
- W1987060400 hasPublicationYear "1994" @default.
- W1987060400 type Work @default.
- W1987060400 sameAs 1987060400 @default.
- W1987060400 citedByCount "179" @default.
- W1987060400 countsByYear W19870604002012 @default.
- W1987060400 countsByYear W19870604002013 @default.
- W1987060400 countsByYear W19870604002014 @default.
- W1987060400 countsByYear W19870604002015 @default.
- W1987060400 countsByYear W19870604002016 @default.
- W1987060400 countsByYear W19870604002017 @default.
- W1987060400 countsByYear W19870604002018 @default.
- W1987060400 countsByYear W19870604002019 @default.
- W1987060400 countsByYear W19870604002020 @default.
- W1987060400 countsByYear W19870604002021 @default.
- W1987060400 countsByYear W19870604002022 @default.
- W1987060400 countsByYear W19870604002023 @default.
- W1987060400 crossrefType "journal-article" @default.
- W1987060400 hasAuthorship W1987060400A5012160968 @default.
- W1987060400 hasAuthorship W1987060400A5023734653 @default.
- W1987060400 hasAuthorship W1987060400A5024852195 @default.
- W1987060400 hasAuthorship W1987060400A5041872479 @default.
- W1987060400 hasAuthorship W1987060400A5044316474 @default.
- W1987060400 hasAuthorship W1987060400A5058922646 @default.
- W1987060400 hasBestOaLocation W19870604001 @default.
- W1987060400 hasConcept C142724271 @default.
- W1987060400 hasConcept C203014093 @default.
- W1987060400 hasConcept C2522874641 @default.
- W1987060400 hasConcept C2776995267 @default.
- W1987060400 hasConcept C2777575956 @default.
- W1987060400 hasConcept C2778751314 @default.
- W1987060400 hasConcept C2779338263 @default.
- W1987060400 hasConcept C2780252810 @default.
- W1987060400 hasConcept C2781059491 @default.
- W1987060400 hasConcept C2781375147 @default.
- W1987060400 hasConcept C71924100 @default.
- W1987060400 hasConceptScore W1987060400C142724271 @default.
- W1987060400 hasConceptScore W1987060400C203014093 @default.
- W1987060400 hasConceptScore W1987060400C2522874641 @default.
- W1987060400 hasConceptScore W1987060400C2776995267 @default.
- W1987060400 hasConceptScore W1987060400C2777575956 @default.
- W1987060400 hasConceptScore W1987060400C2778751314 @default.
- W1987060400 hasConceptScore W1987060400C2779338263 @default.
- W1987060400 hasConceptScore W1987060400C2780252810 @default.
- W1987060400 hasConceptScore W1987060400C2781059491 @default.
- W1987060400 hasConceptScore W1987060400C2781375147 @default.
- W1987060400 hasConceptScore W1987060400C71924100 @default.
- W1987060400 hasIssue "7" @default.
- W1987060400 hasLocation W19870604001 @default.
- W1987060400 hasLocation W19870604002 @default.
- W1987060400 hasOpenAccess W1987060400 @default.
- W1987060400 hasPrimaryLocation W19870604001 @default.
- W1987060400 hasRelatedWork W1989895684 @default.
- W1987060400 hasRelatedWork W2004892826 @default.
- W1987060400 hasRelatedWork W2030238129 @default.
- W1987060400 hasRelatedWork W2059776126 @default.
- W1987060400 hasRelatedWork W2142646234 @default.
- W1987060400 hasRelatedWork W2157436763 @default.
- W1987060400 hasRelatedWork W2339535449 @default.
- W1987060400 hasRelatedWork W2417813779 @default.
- W1987060400 hasRelatedWork W2418511418 @default.
- W1987060400 hasRelatedWork W2755325205 @default.
- W1987060400 hasVolume "25" @default.
- W1987060400 isParatext "false" @default.
- W1987060400 isRetracted "false" @default.
- W1987060400 magId "1987060400" @default.
- W1987060400 workType "article" @default.