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- W1987071402 abstract "Human volunteers were infused with 3H- and 2H-labeled prostacyclin or 3H-labeled 6-ketoprostaglandin F1α and, in separate experiments, with the unlabeled prostanoids. The urine was purified by different chromatographic steps and finally separated into several fractions by high-performance liquid chromatography. The major fractions contained 20.5 and 23.0% of the eluted radioactivity for the metabolites of prostacyclin and 6-ketoprostaglandin F1α, respectively. The structure of both metabolites was identified by gas-liquid chromatography-mass spectrometry as dinor-6-ketoprostaglandin F1α. It is concluded that the major metabolite of prostacyclin and 6-ketoprostaglandin F1α in man is dinor-6-ketoprostaglandin F1α." @default.
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- W1987071402 date "1980-08-01" @default.
- W1987071402 modified "2023-10-16" @default.
- W1987071402 title "Identification of the major metabolite of prostacyclin and 6-ketoprostaglandin F1α in man" @default.
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- W1987071402 doi "https://doi.org/10.1016/0005-2760(80)90069-7" @default.
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