FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987097774> ?p ?o ?g. }

• W1987097774 endingPage "1159" @default.
• W1987097774 startingPage "1155" @default.
• W1987097774 abstract "We describe the synthesis, characterization and radiochemical studies on macroporous chelating polymer beads as carriers of beta-emitters lutetium-177 and iodine-131 intended for radioembolization of liver tumors. The starting poly(glycidyl methacrylate-co-ethylene dimethacrylate) (bead size 20–40 μ) was reacted with ammonia or methylamine to introduce primary and secondary amino groups, respectively. The primary amino groups containing polymer was used for the attachment of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) moieties, while quinoline-8-ol or 8-hydroxyquinoline-5-sulfonic acid moieties, respectively, were introduced onto the secondary amino groups containing polymer. All the polymers were labeled quantitatively by lutetium-177 in ammonium acetate buffer, DOTA containing beads however required heating to 80 °C while the quinoline-8-ol or 8-hydroxyquinoline-5-sulfonic acid moieties containing polymers were quantitatively radiolabeled within 1 h at room temperature. The quinoline-8-ol groups containing polymer was radioiodinated in 95% yield by a chloramine method. Both lutetium-177 and iodine-131 radiolabels were stable in an in vitro study in rat blood plasma. Quinoline-8-ol or 8-hydroxyquinoline-5-sulfonic acid moieties are thus more suitable for the radiolabeling of macroporous beads with lutetium-177 for radioembolization purposes than well-established DOTA moieties and in addition, quinoline-8-ol also allows radiolabeling with iodine-131." @default.
• W1987097774 created "2016-06-24" @default.
• W1987097774 creator A5001457912 @default.
• W1987097774 creator A5010371395 @default.
• W1987097774 creator A5023249817 @default.
• W1987097774 creator A5043955960 @default.
• W1987097774 creator A5046261529 @default.
• W1987097774 creator A5049177551 @default.
• W1987097774 creator A5049285778 @default.
• W1987097774 creator A5070428613 @default.
• W1987097774 date "2011-12-01" @default.
• W1987097774 modified "2023-10-01" @default.
• W1987097774 title "Lutetium-177 and iodine-131 loaded chelating polymer microparticles intended for radioembolization of liver malignancies" @default.
• W1987097774 cites W1544855397 @default.
• W1987097774 cites W1975154077 @default.
• W1987097774 cites W1975750011 @default.
• W1987097774 cites W2019398636 @default.
• W1987097774 cites W2020769496 @default.
• W1987097774 cites W2023934088 @default.
• W1987097774 cites W2027598484 @default.
• W1987097774 cites W2037604854 @default.
• W1987097774 cites W2050410315 @default.
• W1987097774 cites W2064106995 @default.
• W1987097774 cites W2073855339 @default.
• W1987097774 cites W2074473173 @default.
• W1987097774 cites W2081176013 @default.
• W1987097774 cites W2088591216 @default.
• W1987097774 cites W2103637700 @default.
• W1987097774 cites W2114419400 @default.
• W1987097774 cites W2169874604 @default.
• W1987097774 cites W4243625103 @default.
• W1987097774 doi "https://doi.org/10.1016/j.reactfunctpolym.2011.09.003" @default.
• W1987097774 hasPublicationYear "2011" @default.
• W1987097774 type Work @default.
• W1987097774 sameAs 1987097774 @default.
• W1987097774 citedByCount "8" @default.
• W1987097774 countsByYear W19870977742012 @default.
• W1987097774 countsByYear W19870977742013 @default.
• W1987097774 countsByYear W19870977742015 @default.
• W1987097774 countsByYear W19870977742018 @default.
• W1987097774 countsByYear W19870977742021 @default.
• W1987097774 countsByYear W19870977742023 @default.
• W1987097774 crossrefType "journal-article" @default.
• W1987097774 hasAuthorship W1987097774A5001457912 @default.
• W1987097774 hasAuthorship W1987097774A5010371395 @default.
• W1987097774 hasAuthorship W1987097774A5023249817 @default.
• W1987097774 hasAuthorship W1987097774A5043955960 @default.
• W1987097774 hasAuthorship W1987097774A5046261529 @default.
• W1987097774 hasAuthorship W1987097774A5049177551 @default.
• W1987097774 hasAuthorship W1987097774A5049285778 @default.
• W1987097774 hasAuthorship W1987097774A5070428613 @default.
• W1987097774 hasConcept C13965031 @default.
• W1987097774 hasConcept C177322064 @default.
• W1987097774 hasConcept C178790620 @default.
• W1987097774 hasConcept C185592680 @default.
• W1987097774 hasConcept C188027245 @default.
• W1987097774 hasConcept C197404232 @default.
• W1987097774 hasConcept C2775842073 @default.
• W1987097774 hasConcept C2776309666 @default.
• W1987097774 hasConcept C2776970183 @default.
• W1987097774 hasConcept C2778502040 @default.
• W1987097774 hasConcept C2779851234 @default.
• W1987097774 hasConcept C2779931791 @default.
• W1987097774 hasConcept C2989005 @default.
• W1987097774 hasConcept C520551903 @default.
• W1987097774 hasConcept C521977710 @default.
• W1987097774 hasConcept C531131001 @default.
• W1987097774 hasConcept C557651011 @default.
• W1987097774 hasConcept C71924100 @default.
• W1987097774 hasConceptScore W1987097774C13965031 @default.
• W1987097774 hasConceptScore W1987097774C177322064 @default.
• W1987097774 hasConceptScore W1987097774C178790620 @default.
• W1987097774 hasConceptScore W1987097774C185592680 @default.
• W1987097774 hasConceptScore W1987097774C188027245 @default.
• W1987097774 hasConceptScore W1987097774C197404232 @default.
• W1987097774 hasConceptScore W1987097774C2775842073 @default.
• W1987097774 hasConceptScore W1987097774C2776309666 @default.
• W1987097774 hasConceptScore W1987097774C2776970183 @default.
• W1987097774 hasConceptScore W1987097774C2778502040 @default.
• W1987097774 hasConceptScore W1987097774C2779851234 @default.
• W1987097774 hasConceptScore W1987097774C2779931791 @default.
• W1987097774 hasConceptScore W1987097774C2989005 @default.
• W1987097774 hasConceptScore W1987097774C520551903 @default.
• W1987097774 hasConceptScore W1987097774C521977710 @default.
• W1987097774 hasConceptScore W1987097774C531131001 @default.
• W1987097774 hasConceptScore W1987097774C557651011 @default.
• W1987097774 hasConceptScore W1987097774C71924100 @default.
• W1987097774 hasFunder F4320321005 @default.
• W1987097774 hasFunder F4320321006 @default.
• W1987097774 hasIssue "12" @default.
• W1987097774 hasLocation W19870977741 @default.
• W1987097774 hasOpenAccess W1987097774 @default.
• W1987097774 hasPrimaryLocation W19870977741 @default.
• W1987097774 hasRelatedWork W2022977216 @default.
• W1987097774 hasRelatedWork W2056321700 @default.
• W1987097774 hasRelatedWork W2070969573 @default.
• W1987097774 hasRelatedWork W2072731349 @default.
• W1987097774 hasRelatedWork W2093483406 @default.

• next