FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987104278> ?p ?o ?g. }

• W1987104278 endingPage "252" @default.
• W1987104278 startingPage "247" @default.
• W1987104278 abstract "Abstract The prospective multicenter NOA‐03 trial, conducted by the Neuro‐Oncology Working Group (NOA) of the German Cancer Society, was initiated to define the feasibility and efficacy of single‐agent high‐dose methotrexate therapy without concomitant radiotherapy in immunocompetent patients with primary central nervous system lymphoma. Thirty‐seven patients (median age, 60 years) received 179 biweekly courses of 8g/m 2 methotrexate. Response was assessed after 3 and 6 courses. We had planned to enter 105 patients into the trial. Since fewer than the projected 18 of 37 patients achieved a complete response after an intermediate analysis, the trial was closed. In intention‐to‐treat analysis, 11 of 37 patients (29.7%) achieved complete response, whereas 14 of 37 patients (37.8%) were found to have progressive disease. The median relapse‐free survival among complete response patients was 13.7 months. Multivariate logistic regression analysis revealed that corticosteroid application during the first methotrexate course was associated with complete response. The regimen was well tolerated, but, unlike previously reported results, the activity of high‐dose methotrexate was only moderate." @default.
• W1987104278 created "2016-06-24" @default.
• W1987104278 creator A5007982767 @default.
• W1987104278 creator A5017177249 @default.
• W1987104278 creator A5019082343 @default.
• W1987104278 creator A5025900662 @default.
• W1987104278 creator A5029197290 @default.
• W1987104278 creator A5030332648 @default.
• W1987104278 creator A5042780466 @default.
• W1987104278 creator A5045576410 @default.
• W1987104278 creator A5053357127 @default.
• W1987104278 creator A5059340935 @default.
• W1987104278 creator A5066290988 @default.
• W1987104278 creator A5066624700 @default.
• W1987104278 creator A5069752650 @default.
• W1987104278 creator A5080392503 @default.
• W1987104278 creator A5085820448 @default.
• W1987104278 creator A5088049440 @default.
• W1987104278 creator A5088372883 @default.
• W1987104278 date "2002-01-31" @default.
• W1987104278 modified "2023-10-18" @default.
• W1987104278 title "German Cancer Society Neuro-Oncology Working Group NOA-03 multicenter trial of single-agent high-dose methotrexate for primary central nervous system lymphoma" @default.
• W1987104278 cites W1480952979 @default.
• W1987104278 cites W1839979783 @default.
• W1987104278 cites W1860711823 @default.
• W1987104278 cites W1862506306 @default.
• W1987104278 cites W1959628099 @default.
• W1987104278 cites W1969695259 @default.
• W1987104278 cites W1979297906 @default.
• W1987104278 cites W1998819691 @default.
• W1987104278 cites W1998885120 @default.
• W1987104278 cites W2026908425 @default.
• W1987104278 cites W2062968968 @default.
• W1987104278 cites W2159708587 @default.
• W1987104278 cites W2179658416 @default.
• W1987104278 cites W2186111039 @default.
• W1987104278 cites W2202266713 @default.
• W1987104278 cites W4251098676 @default.
• W1987104278 cites W4293241248 @default.
• W1987104278 doi "https://doi.org/10.1002/ana.10102" @default.
• W1987104278 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11835382" @default.
• W1987104278 hasPublicationYear "2002" @default.
• W1987104278 type Work @default.
• W1987104278 sameAs 1987104278 @default.
• W1987104278 citedByCount "166" @default.
• W1987104278 countsByYear W19871042782012 @default.
• W1987104278 countsByYear W19871042782013 @default.
• W1987104278 countsByYear W19871042782014 @default.
• W1987104278 countsByYear W19871042782015 @default.
• W1987104278 countsByYear W19871042782016 @default.
• W1987104278 countsByYear W19871042782017 @default.
• W1987104278 countsByYear W19871042782018 @default.
• W1987104278 countsByYear W19871042782019 @default.
• W1987104278 countsByYear W19871042782020 @default.
• W1987104278 countsByYear W19871042782021 @default.
• W1987104278 countsByYear W19871042782022 @default.
• W1987104278 countsByYear W19871042782023 @default.
• W1987104278 crossrefType "journal-article" @default.
• W1987104278 hasAuthorship W1987104278A5007982767 @default.
• W1987104278 hasAuthorship W1987104278A5017177249 @default.
• W1987104278 hasAuthorship W1987104278A5019082343 @default.
• W1987104278 hasAuthorship W1987104278A5025900662 @default.
• W1987104278 hasAuthorship W1987104278A5029197290 @default.
• W1987104278 hasAuthorship W1987104278A5030332648 @default.
• W1987104278 hasAuthorship W1987104278A5042780466 @default.
• W1987104278 hasAuthorship W1987104278A5045576410 @default.
• W1987104278 hasAuthorship W1987104278A5053357127 @default.
• W1987104278 hasAuthorship W1987104278A5059340935 @default.
• W1987104278 hasAuthorship W1987104278A5066290988 @default.
• W1987104278 hasAuthorship W1987104278A5066624700 @default.
• W1987104278 hasAuthorship W1987104278A5069752650 @default.
• W1987104278 hasAuthorship W1987104278A5080392503 @default.
• W1987104278 hasAuthorship W1987104278A5085820448 @default.
• W1987104278 hasAuthorship W1987104278A5088049440 @default.
• W1987104278 hasAuthorship W1987104278A5088372883 @default.
• W1987104278 hasConcept C126322002 @default.
• W1987104278 hasConcept C141071460 @default.
• W1987104278 hasConcept C143998085 @default.
• W1987104278 hasConcept C168563851 @default.
• W1987104278 hasConcept C2775965419 @default.
• W1987104278 hasConcept C2776694085 @default.
• W1987104278 hasConcept C2778336483 @default.
• W1987104278 hasConcept C2779384505 @default.
• W1987104278 hasConcept C2781059491 @default.
• W1987104278 hasConcept C2781173314 @default.
• W1987104278 hasConcept C2781413609 @default.
• W1987104278 hasConcept C2992435398 @default.
• W1987104278 hasConcept C509974204 @default.
• W1987104278 hasConcept C535046627 @default.
• W1987104278 hasConcept C71924100 @default.
• W1987104278 hasConceptScore W1987104278C126322002 @default.
• W1987104278 hasConceptScore W1987104278C141071460 @default.
• W1987104278 hasConceptScore W1987104278C143998085 @default.
• W1987104278 hasConceptScore W1987104278C168563851 @default.
• W1987104278 hasConceptScore W1987104278C2775965419 @default.
• W1987104278 hasConceptScore W1987104278C2776694085 @default.
• W1987104278 hasConceptScore W1987104278C2778336483 @default.
• W1987104278 hasConceptScore W1987104278C2779384505 @default.

• next