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• W1987133368 abstract "Although the study of embryonic kidney development began in the 1950s, three decades passed until scientists began identifying the molecular controls of renal organogenesis. Most of these advances have come from mouse gene targeting and rodent kidney explant manipulation. Translation of the rodent data to human congenital kidney disease has only just begun. The activities of those regulatory molecules proven to be used in common appear remarkably similar in mouse and human renal development. Examples of these genes include glial cell line-derived neurotrophic factor (GDNF), RET, PAX2, Wilms tumor suppressor (WT1), and components in the renin–angiotensin pathway. Other factors that participate in mouse renal organogenesis, such as N-Myc, may later be proven important in human kidney development." @default.
• W1987133368 created "2016-06-24" @default.
• W1987133368 creator A5059246094 @default.
• W1987133368 date "2000-09-01" @default.
• W1987133368 modified "2023-10-16" @default.
• W1987133368 title "Kidney Development: Regulatory Molecules Crucial to Both Mice and Men" @default.
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• W1987133368 doi "https://doi.org/10.1006/mgme.2000.3072" @default.
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