FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987135462> ?p ?o ?g. }

• W1987135462 endingPage "535" @default.
• W1987135462 startingPage "529" @default.
• W1987135462 abstract "Cystic fibrosis (CF) patients are predisposed to chronic respiratory infection by nonfermentative gram-negative bacilli, including Stenotrophomonas maltophilia. S. maltophilia is highly resistant to most antibiotics, with the exception of sulfamethoxazole-trimethoprim (SXT). SXT-resistant S. maltophilia has been reported, but the mechanism of resistance is not well defined. Repeated findings of suspected small-colony-variant (SCV) S. maltophilia isolates from the sputa of five CF patients were confirmed by partial 16S rRNA gene sequencing. The SCV S. maltophilia isolates were the only S. maltophilia isolates in these cultures, and none were clonally related. DNA fingerprint analysis confirmed that once established, the SCV S. maltophilia strains persisted. Nutritional studies of SCV S. maltophilia have suggested auxotrophy in hemin, methionine, and thymidine associated with resistance to multiple antibiotics, including SXT. The phenotypic switch from wild-type to SCV S. maltophilia was reproducible in vitro by exposure to SXT, suggesting that prolonged exposure to antibiotics may select for both the SCV S. maltophilia phenotype and SXT resistance by interference with the dihydrofolate reductase pathway. Recovery of SCV S. maltophilia from the sputum of CF patients has implications for both laboratory testing and patient management." @default.
• W1987135462 created "2016-06-24" @default.
• W1987135462 creator A5000114104 @default.
• W1987135462 creator A5020905593 @default.
• W1987135462 creator A5072954834 @default.
• W1987135462 creator A5077615947 @default.
• W1987135462 date "2007-02-01" @default.
• W1987135462 modified "2023-10-01" @default.
• W1987135462 title "Characterization of Small-Colony-Variant <i>Stenotrophomonas maltophilia</i> Isolated from the Sputum Specimens of Five Patients with Cystic Fibrosis" @default.
• W1987135462 cites W1543289866 @default.
• W1987135462 cites W1586204120 @default.
• W1987135462 cites W1851388668 @default.
• W1987135462 cites W1981479453 @default.
• W1987135462 cites W1999277244 @default.
• W1987135462 cites W2027373007 @default.
• W1987135462 cites W2052899289 @default.
• W1987135462 cites W2053841039 @default.
• W1987135462 cites W2059184280 @default.
• W1987135462 cites W2062689424 @default.
• W1987135462 cites W2078078890 @default.
• W1987135462 cites W2078685101 @default.
• W1987135462 cites W2088960594 @default.
• W1987135462 cites W2114660268 @default.
• W1987135462 cites W2117621673 @default.
• W1987135462 cites W2131545560 @default.
• W1987135462 cites W2147695950 @default.
• W1987135462 cites W2153133935 @default.
• W1987135462 cites W2155246554 @default.
• W1987135462 cites W2165022453 @default.
• W1987135462 cites W3136726370 @default.
• W1987135462 doi "https://doi.org/10.1128/jcm.01444-06" @default.
• W1987135462 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1829025" @default.
• W1987135462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17135443" @default.
• W1987135462 hasPublicationYear "2007" @default.
• W1987135462 type Work @default.
• W1987135462 sameAs 1987135462 @default.
• W1987135462 citedByCount "41" @default.
• W1987135462 countsByYear W19871354622012 @default.
• W1987135462 countsByYear W19871354622013 @default.
• W1987135462 countsByYear W19871354622014 @default.
• W1987135462 countsByYear W19871354622015 @default.
• W1987135462 countsByYear W19871354622016 @default.
• W1987135462 countsByYear W19871354622017 @default.
• W1987135462 countsByYear W19871354622018 @default.
• W1987135462 countsByYear W19871354622019 @default.
• W1987135462 countsByYear W19871354622020 @default.
• W1987135462 countsByYear W19871354622021 @default.
• W1987135462 countsByYear W19871354622022 @default.
• W1987135462 countsByYear W19871354622023 @default.
• W1987135462 crossrefType "journal-article" @default.
• W1987135462 hasAuthorship W1987135462A5000114104 @default.
• W1987135462 hasAuthorship W1987135462A5020905593 @default.
• W1987135462 hasAuthorship W1987135462A5072954834 @default.
• W1987135462 hasAuthorship W1987135462A5077615947 @default.
• W1987135462 hasBestOaLocation W19871354622 @default.
• W1987135462 hasConcept C142724271 @default.
• W1987135462 hasConcept C2776301714 @default.
• W1987135462 hasConcept C2776352461 @default.
• W1987135462 hasConcept C2776938444 @default.
• W1987135462 hasConcept C2777637488 @default.
• W1987135462 hasConcept C2780728791 @default.
• W1987135462 hasConcept C2781069245 @default.
• W1987135462 hasConcept C501593827 @default.
• W1987135462 hasConcept C523546767 @default.
• W1987135462 hasConcept C54355233 @default.
• W1987135462 hasConcept C71924100 @default.
• W1987135462 hasConcept C86803240 @default.
• W1987135462 hasConcept C89423630 @default.
• W1987135462 hasConceptScore W1987135462C142724271 @default.
• W1987135462 hasConceptScore W1987135462C2776301714 @default.
• W1987135462 hasConceptScore W1987135462C2776352461 @default.
• W1987135462 hasConceptScore W1987135462C2776938444 @default.
• W1987135462 hasConceptScore W1987135462C2777637488 @default.
• W1987135462 hasConceptScore W1987135462C2780728791 @default.
• W1987135462 hasConceptScore W1987135462C2781069245 @default.
• W1987135462 hasConceptScore W1987135462C501593827 @default.
• W1987135462 hasConceptScore W1987135462C523546767 @default.
• W1987135462 hasConceptScore W1987135462C54355233 @default.
• W1987135462 hasConceptScore W1987135462C71924100 @default.
• W1987135462 hasConceptScore W1987135462C86803240 @default.
• W1987135462 hasConceptScore W1987135462C89423630 @default.
• W1987135462 hasIssue "2" @default.
• W1987135462 hasLocation W19871354621 @default.
• W1987135462 hasLocation W19871354622 @default.
• W1987135462 hasLocation W19871354623 @default.
• W1987135462 hasLocation W19871354624 @default.
• W1987135462 hasOpenAccess W1987135462 @default.
• W1987135462 hasPrimaryLocation W19871354621 @default.
• W1987135462 hasRelatedWork W1966366103 @default.
• W1987135462 hasRelatedWork W2034003645 @default.
• W1987135462 hasRelatedWork W2040834056 @default.
• W1987135462 hasRelatedWork W2064068126 @default.
• W1987135462 hasRelatedWork W2069898427 @default.
• W1987135462 hasRelatedWork W2141179630 @default.
• W1987135462 hasRelatedWork W2333615353 @default.
• W1987135462 hasRelatedWork W2434948047 @default.
• W1987135462 hasRelatedWork W2783004139 @default.
• W1987135462 hasRelatedWork W2946105220 @default.

• next