FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987136765> ?p ?o ?g. }

• W1987136765 endingPage "1228" @default.
• W1987136765 startingPage "1222" @default.
• W1987136765 abstract "Murine models are commonly used to investigate bone healing and test new treatments before human trials. Our objective was to design an improved murine femur fracture device and determine optimal mass and velocity settings for maximal likelihood of transverse fracture. Fracture reproducibility was maximized using an adjustable kinetic energy level, a novel mouse positioning system and an electromagnet striker release assembly. Sixty wild-type mice of 8-12-week-old male and female with a weight of 26.4+/-6.1g were subjected to an experimental postmortem fracture in the left and right femur (n=120) using variable kinetic energy inputs. A best-fit prediction equation for transverse fracture was developed using multivariate linear regression. Transverse fracture was shown to correlate most highly with kinetic energy with a maximum likelihood at mv2=292 where m is mass (g) and v is velocity (m/s). Model validation with a group of 134 anesthetized C57BL/6 mice resulted in a favorable transverse fracture rate of 85.8%. Simple modifications to existing fracture devices can improve accuracy and reproducibility. The results may assist researchers studying the effects of genetic modifications and novel treatments on boney healing in murine femur fracture models. Maintaining kinetic energy parameters within suggested ranges may also aid in ensuring accuracy and reproducibility." @default.
• W1987136765 created "2016-06-24" @default.
• W1987136765 creator A5016758030 @default.
• W1987136765 creator A5019320244 @default.
• W1987136765 creator A5051609888 @default.
• W1987136765 creator A5067959505 @default.
• W1987136765 creator A5086012730 @default.
• W1987136765 creator A5088755754 @default.
• W1987136765 date "2008-01-01" @default.
• W1987136765 modified "2023-10-17" @default.
• W1987136765 title "An improved murine femur fracture device for bone healing studies" @default.
• W1987136765 cites W1978965889 @default.
• W1987136765 cites W1978966296 @default.
• W1987136765 cites W1979242330 @default.
• W1987136765 cites W1987189093 @default.
• W1987136765 cites W1988221250 @default.
• W1987136765 cites W1991567173 @default.
• W1987136765 cites W2012857475 @default.
• W1987136765 cites W2022824843 @default.
• W1987136765 cites W2038426024 @default.
• W1987136765 cites W2057862617 @default.
• W1987136765 cites W2090230271 @default.
• W1987136765 cites W2090401194 @default.
• W1987136765 cites W2105383153 @default.
• W1987136765 cites W2133559605 @default.
• W1987136765 cites W2147050460 @default.
• W1987136765 cites W2149192174 @default.
• W1987136765 doi "https://doi.org/10.1016/j.jbiomech.2008.01.029" @default.
• W1987136765 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18384794" @default.
• W1987136765 hasPublicationYear "2008" @default.
• W1987136765 type Work @default.
• W1987136765 sameAs 1987136765 @default.
• W1987136765 citedByCount "44" @default.
• W1987136765 countsByYear W19871367652012 @default.
• W1987136765 countsByYear W19871367652013 @default.
• W1987136765 countsByYear W19871367652014 @default.
• W1987136765 countsByYear W19871367652015 @default.
• W1987136765 countsByYear W19871367652016 @default.
• W1987136765 countsByYear W19871367652017 @default.
• W1987136765 countsByYear W19871367652018 @default.
• W1987136765 countsByYear W19871367652019 @default.
• W1987136765 countsByYear W19871367652020 @default.
• W1987136765 countsByYear W19871367652021 @default.
• W1987136765 countsByYear W19871367652022 @default.
• W1987136765 countsByYear W19871367652023 @default.
• W1987136765 crossrefType "journal-article" @default.
• W1987136765 hasAuthorship W1987136765A5016758030 @default.
• W1987136765 hasAuthorship W1987136765A5019320244 @default.
• W1987136765 hasAuthorship W1987136765A5051609888 @default.
• W1987136765 hasAuthorship W1987136765A5067959505 @default.
• W1987136765 hasAuthorship W1987136765A5086012730 @default.
• W1987136765 hasAuthorship W1987136765A5088755754 @default.
• W1987136765 hasConcept C105702510 @default.
• W1987136765 hasConcept C105795698 @default.
• W1987136765 hasConcept C121332964 @default.
• W1987136765 hasConcept C135889238 @default.
• W1987136765 hasConcept C136229726 @default.
• W1987136765 hasConcept C141071460 @default.
• W1987136765 hasConcept C154954056 @default.
• W1987136765 hasConcept C159985019 @default.
• W1987136765 hasConcept C192562407 @default.
• W1987136765 hasConcept C2780554211 @default.
• W1987136765 hasConcept C2992660301 @default.
• W1987136765 hasConcept C33923547 @default.
• W1987136765 hasConcept C43369102 @default.
• W1987136765 hasConcept C62520636 @default.
• W1987136765 hasConcept C71924100 @default.
• W1987136765 hasConcept C8337478 @default.
• W1987136765 hasConcept C9893847 @default.
• W1987136765 hasConceptScore W1987136765C105702510 @default.
• W1987136765 hasConceptScore W1987136765C105795698 @default.
• W1987136765 hasConceptScore W1987136765C121332964 @default.
• W1987136765 hasConceptScore W1987136765C135889238 @default.
• W1987136765 hasConceptScore W1987136765C136229726 @default.
• W1987136765 hasConceptScore W1987136765C141071460 @default.
• W1987136765 hasConceptScore W1987136765C154954056 @default.
• W1987136765 hasConceptScore W1987136765C159985019 @default.
• W1987136765 hasConceptScore W1987136765C192562407 @default.
• W1987136765 hasConceptScore W1987136765C2780554211 @default.
• W1987136765 hasConceptScore W1987136765C2992660301 @default.
• W1987136765 hasConceptScore W1987136765C33923547 @default.
• W1987136765 hasConceptScore W1987136765C43369102 @default.
• W1987136765 hasConceptScore W1987136765C62520636 @default.
• W1987136765 hasConceptScore W1987136765C71924100 @default.
• W1987136765 hasConceptScore W1987136765C8337478 @default.
• W1987136765 hasConceptScore W1987136765C9893847 @default.
• W1987136765 hasIssue "6" @default.
• W1987136765 hasLocation W19871367651 @default.
• W1987136765 hasLocation W19871367652 @default.
• W1987136765 hasOpenAccess W1987136765 @default.
• W1987136765 hasPrimaryLocation W19871367651 @default.
• W1987136765 hasRelatedWork W1634416457 @default.
• W1987136765 hasRelatedWork W1987136765 @default.
• W1987136765 hasRelatedWork W1992301735 @default.
• W1987136765 hasRelatedWork W2032583168 @default.
• W1987136765 hasRelatedWork W2339271071 @default.
• W1987136765 hasRelatedWork W2362317606 @default.
• W1987136765 hasRelatedWork W2378918332 @default.

• next