Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987144477> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W1987144477 endingPage "274" @default.
- W1987144477 startingPage "265" @default.
- W1987144477 abstract "Cytoplasmic DNA-binding proteins were isolated from Chinese hamster liver, kidney and tissue culture cells by DNA-polyacrylamide chromatography. With homologous Chinese hamster DNA, and with calf thymus DNA, 1.4% of the proteins were bound to the column. With single-stranded DNA and with heterologous Micrococcus lysodeikticus DNA there was only 0.3% binding, suggesting the proteins preferentially bind to double-stranded DNA and show some sequence specificity. By a nitrocellulose filter assay the bound proteins had at least a 4- to 7-fold greater affinity for DNA than bulk cytoplasmic protein. SDS gel electrophoresis showed that specific proteins were being markedly concentrated by the column and it was primarily the high molecular weight proteins of 65 000 D and over which showed sequence specificity. Some proteins appeared in common with different organs, others were unique. These studies thus define a group of high molecular weight, cytoplasmic proteins which bind to native DNA with a degree of sequence specificity. Their possible relationship to gene regulation is discussed." @default.
- W1987144477 created "2016-06-24" @default.
- W1987144477 creator A5036298177 @default.
- W1987144477 creator A5090786516 @default.
- W1987144477 date "1973-08-01" @default.
- W1987144477 modified "2023-09-27" @default.
- W1987144477 title "Cytoplasmic DNA-binding proteins" @default.
- W1987144477 cites W1485128548 @default.
- W1987144477 cites W1542243713 @default.
- W1987144477 cites W1573008071 @default.
- W1987144477 cites W1625660792 @default.
- W1987144477 cites W1979607828 @default.
- W1987144477 cites W2001332675 @default.
- W1987144477 cites W2026663541 @default.
- W1987144477 cites W2031197718 @default.
- W1987144477 cites W2037548855 @default.
- W1987144477 cites W2038620193 @default.
- W1987144477 cites W2054496266 @default.
- W1987144477 cites W2087594882 @default.
- W1987144477 cites W2090087678 @default.
- W1987144477 cites W209659648 @default.
- W1987144477 cites W2162158840 @default.
- W1987144477 cites W2167257469 @default.
- W1987144477 cites W2495783190 @default.
- W1987144477 cites W94861071 @default.
- W1987144477 doi "https://doi.org/10.1016/0014-4827(73)90296-6" @default.
- W1987144477 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4745375" @default.
- W1987144477 hasPublicationYear "1973" @default.
- W1987144477 type Work @default.
- W1987144477 sameAs 1987144477 @default.
- W1987144477 citedByCount "15" @default.
- W1987144477 crossrefType "journal-article" @default.
- W1987144477 hasAuthorship W1987144477A5036298177 @default.
- W1987144477 hasAuthorship W1987144477A5090786516 @default.
- W1987144477 hasConcept C101762097 @default.
- W1987144477 hasConcept C104317684 @default.
- W1987144477 hasConcept C116084860 @default.
- W1987144477 hasConcept C150194340 @default.
- W1987144477 hasConcept C153911025 @default.
- W1987144477 hasConcept C190062978 @default.
- W1987144477 hasConcept C3662595 @default.
- W1987144477 hasConcept C552990157 @default.
- W1987144477 hasConcept C55493867 @default.
- W1987144477 hasConcept C86339819 @default.
- W1987144477 hasConcept C86803240 @default.
- W1987144477 hasConcept C94966510 @default.
- W1987144477 hasConceptScore W1987144477C101762097 @default.
- W1987144477 hasConceptScore W1987144477C104317684 @default.
- W1987144477 hasConceptScore W1987144477C116084860 @default.
- W1987144477 hasConceptScore W1987144477C150194340 @default.
- W1987144477 hasConceptScore W1987144477C153911025 @default.
- W1987144477 hasConceptScore W1987144477C190062978 @default.
- W1987144477 hasConceptScore W1987144477C3662595 @default.
- W1987144477 hasConceptScore W1987144477C552990157 @default.
- W1987144477 hasConceptScore W1987144477C55493867 @default.
- W1987144477 hasConceptScore W1987144477C86339819 @default.
- W1987144477 hasConceptScore W1987144477C86803240 @default.
- W1987144477 hasConceptScore W1987144477C94966510 @default.
- W1987144477 hasIssue "2" @default.
- W1987144477 hasLocation W19871444771 @default.
- W1987144477 hasLocation W19871444772 @default.
- W1987144477 hasOpenAccess W1987144477 @default.
- W1987144477 hasPrimaryLocation W19871444771 @default.
- W1987144477 hasRelatedWork W140137319 @default.
- W1987144477 hasRelatedWork W1982917919 @default.
- W1987144477 hasRelatedWork W1983626749 @default.
- W1987144477 hasRelatedWork W2009673058 @default.
- W1987144477 hasRelatedWork W2053402793 @default.
- W1987144477 hasRelatedWork W2141036280 @default.
- W1987144477 hasRelatedWork W2227516629 @default.
- W1987144477 hasRelatedWork W2397468087 @default.
- W1987144477 hasRelatedWork W33951803 @default.
- W1987144477 hasRelatedWork W4236942977 @default.
- W1987144477 hasVolume "80" @default.
- W1987144477 isParatext "false" @default.
- W1987144477 isRetracted "false" @default.
- W1987144477 magId "1987144477" @default.
- W1987144477 workType "article" @default.