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- W1987147922 abstract "Abstract The secreted and cell surface immunoglobulin of a Syrian hamster plasmacytoma (PLA-1) were studied. Secreted immunoglobulin was internally labeled by metabolic incorporation of 3H-amino acids. Cell surface immunoglobulin was labeled with 125I by the lactoperoxidase method. The major secreted product was shown to be IgA and to possess heavy chains of approximately 60,000–68,000 daltons and light chains of 23,000 daltons. Cell surface immunoglobulin reacted only weakly with anti-IgA reagents, had an apparent mol. wt of 250,000 daltons and possessed heavy chains of 90,000–98,000 daltons and light chains of 23,000 daltons. Therefore, the secreted product of PLA-1 appears to be very similar to normal secreted immunoglobulin while the cell surface immunoglobulin appears to be unusual, containing heavy chains that differ in size and relative antigenicity from normal serum immunoglobulin and in-vitro secretions." @default.
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- W1987147922 date "1979-08-01" @default.
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- W1987147922 title "Unusual cell surface immunoglobulin on a plasma cell tumor" @default.
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- W1987147922 doi "https://doi.org/10.1016/0161-5890(79)90114-7" @default.
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