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• W1987166893 abstract "Human Gene TherapyVol. 7, No. 10 News and CommentsGene Therapy for AIDS Using Retroviral Mediated Gene Transfer to Deliver HIV-1 Antisense TAR and Transdominant Rev Protein Genes to Syngeneic Lymphocytes in HIV-1 Infected Identical Twins. National Institutes of Health, Bethesda, MarylandPRINCIPAL INVESTIGATOR Richard A. Morgan and MEDICALLY RESPONSIBLE INVESTIGATOR Robert WalkerPRINCIPAL INVESTIGATOR Richard A. MorganSearch for more papers by this author and MEDICALLY RESPONSIBLE INVESTIGATOR Robert WalkerSearch for more papers by this authorPublished Online:20 Mar 2008https://doi.org/10.1089/hum.1996.7.10-1281AboutSectionsPDF/EPUB ToolsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail FiguresReferencesRelatedDetailsCited ByCould gene therapy cure HIV?Life Sciences, Vol. 277HIV Gene Therapy: An Update Tatjana I. Cornu, Claudio Mussolino, Matthias C. Müller, Claudia Wehr, Winfried V. Kern, and Toni Cathomen18 January 2021 | Human Gene Therapy, Vol. 32, No. 1-2Advances toward Curing HIV-1 Infection in Tissue ReservoirsJournal of Virology, Vol. 94, No. 3Efficient Transduction of Human and Rhesus Macaque Primary T Cells by a Modified Human Immunodeficiency Virus Type 1–Based Lentiviral Vector Huan He, Jing Xue, Weiming Wang, Lihong Liu, Chaobaihui Ye, Zhe Cong, Jason T. Kimata, Chuan Qin, and Paul Zhou1 March 2017 | Human Gene Therapy, Vol. 28, No. 3HIV and Stem Cell Transplantation14 August 2014 | Current Infectious Disease Reports, Vol. 16, No. 9The enhancement of RNAi against HIV in vitro and in vivo using H-2Kk protein as a sorting methodJournal of Virological Methods, Vol. 182, No. 1-2Patients with Human Immunodeficiency Virus: Hematopoeitic Stem Cell Transplantation27 January 2012Allogeneic haematopoietic stem cell transplantation in patients with human immunodeficiency virus: the experiences of more than 25 years8 February 2011 | Clinical and Experimental Immunology, Vol. 163, No. 3Clinical Applications of Gene TherapyLong-Term Vector Integration Site Analysis Following Retroviral Mediated Gene Transfer to Hematopoietic Stem Cells for the Treatment of HIV Infection16 January 2009 | PLoS ONE, Vol. 4, No. 1Gene Therapy to Induce Cellular Resistance to HIV‐1 Infection: Lessons from Clinical TrialsFoamy Virus Vectors Expressing Anti-HIV Transgenes Efficiently Block HIV-1 ReplicationMolecular Therapy, Vol. 16, No. 1Development of targeted gene transfer into human primary T lymphocytes and macrophages using high-titer recombinant HIV vectorsJournal of Biotechnology, Vol. 129, No. 3Delivery of double-stranded DNA thioaptamers into HIV-1 infected cells for antiviral activityBiochemical and Biophysical Research Communications, Vol. 344, No. 3Musculoskeletal Gene Therapy and its Potential Use in the Treatment of Complicated Musculoskeletal InfectionInfectious Disease Clinics of North America, Vol. 19, No. 4Suppression of Human Immunodeficiency Virus Type 1 (HIV-1) Replication by an HIV-1-dependent Double Locked Vector with the Cre/loxP System16 August 2006 | Nucleosides, Nucleotides & Nucleic Acids, Vol. 24, No. 10-12Current status of gene therapy strategies to treat HIV/AIDSMolecular Therapy, Vol. 11, No. 6Antisense-Mediated Inhibition of Human Immunodeficiency Virus (HIV) Replication by Use of an HIV Type 1-Based Vector Results in Severely Attenuated Mutants Incapable of Developing ResistanceJournal of Virology, Vol. 78, No. 13Gene therapy for HIV/AIDS: the potential for a new therapeutic regimen1 January 2003 | The Journal of Gene Medicine, Vol. 5, No. 8Recombinant human antibodies against the reverse transcriptase of human immunodeficiency virus type-1Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, Vol. 1648, No. 1-2Inhibition of HIV-1 replication in primary human T cells transduced with an intracellular anti-HIV-1 p17 antibody gene1 January 2003 | The Journal of Gene Medicine, Vol. 5, No. 3Problems and solutions to successful gene-transfer based therapies for HIVClinical and Applied Immunology Reviews, Vol. 3, No. 4-5Gene Therapy–based Treatment for HIV-Positive Patients with Malignancies Elizabeth M. Kang, Moniek de Witte, Harry Malech, Richard A. Morgan, Charles Carter, Susan F. Leitman, Richard Childs, A. John Barrett, Richard Little, and John F. Tisdale9 July 2004 | Journal of Hematotherapy & Stem Cell Research, Vol. 11, No. 5Additive and antagonist effects of therapeutic gene combinations for suppression of HIV-1 infectionAntiviral Research, Vol. 55, No. 1Lentiviral transduction of human T-lymphocytes with a RANTES intrakine inhibits human immunodeficiency virus type 1 infection18 June 2002 | Gene Therapy, Vol. 9, No. 13Design of HIV Vectors for Efficient Gene Delivery into Human Hematopoietic CellsMolecular Therapy, Vol. 5, No. 4Inhibition of HIV-1 replication by novel lentiviral vectors expressing transdominant Rev and HIV-1 env antisense10 April 2002 | Gene Therapy, Vol. 9, No. 7Nonmyeloablative conditioning followed by transplantation of genetically modified HLA-matched peripheral blood progenitor cells for hematologic malignancies in patients with acquired immunodeficiency syndromeBlood, Vol. 99, No. 2Gene Therapy Approaches to HIV InfectionAmerican Journal of PharmacoGenomics, Vol. 2, No. 4High-Efficiency Gene Transfer into Rhesus Macaque Primary T Lymphocytes by Combining 32°C Centrifugation and CH-296-Coated Plates: Effect of Gene Transfer Protocol on T Cell Homing Receptor Expression Paul Zhou, Joonhaeng Lee, Patina Moore, and Kathleen M. Brasky6 July 2004 | Human Gene Therapy, Vol. 12, No. 15Induction of Potent Human Immunodeficiency Virus Type 1-Specific T-Cell-Restricted Immunity by Genetically Modified Dendritic CellsJournal of Virology, Vol. 75, No. 16Gene therapyBiotechnology Advances, Vol. 19, No. 4Inhibition of Human Immunodeficiency Virus Type 1 (HIV-1) Replication by HIV-1-Based Lentivirus Vectors Expressing Transdominant RevJournal of Virology, Vol. 75, No. 8Selective Killing of Human Immunodeficiency Virus-Infected Cells by Targeted Gene Transfer and Inducible Gene Expression Using a Recombinant Human Immunodeficiency Virus Vector Koichi Miyake, Osamu Iijima, Noriko Suzuki, Makoto Matsukura, and Takashi Shimada6 July 2004 | Human Gene Therapy, Vol. 12, No. 3Hematologic Aspects of HIV/AIDSHematology, Vol. 2001, No. 1THE POTENTIAL FOR THERAPY OF IMMUNE DISORDERS WITH GENE THERAPYPediatric Clinics of North America, Vol. 47, No. 6Potent Inhibition of Human Immunodeficiency Virus Type 1 Replication by Conditionally Replicating Human Immunodeficiency Virus-Based Lentiviral Vectors Expressing Envelope Antisense mRNA Mario R. Mautino and Richard A. Morgan6 July 2004 | Human Gene Therapy, Vol. 11, No. 14Modified Human Immunodeficiency Virus-Based Lentiviral Vectors Display Decreased Sensitivity to Trans-Dominant Rev Mario R. Mautino, W. Jay Ramsey, Jakob Reiser, and Richard A. Morgan6 July 2004 | Human Gene Therapy, Vol. 11, No. 6Human T Lymphocyte Genetic Modification with Naked DNAMolecular Therapy, Vol. 1, No. 1Therapies directed against the rev axis of HIV autoregulationInhibition of Human Immunodeficiency Virus Replication and Growth Advantage of CD4+ T Cells and Monocytes Derived from CD34+ Cells Transduced with an Intracellular Antibody Directed against Human Immunodeficiency Virus Type 1 Tat Mark C. Poznansky, Joyce La Vecchio, Sandra Silva-Arietta, Julie Porter-Brooks, Kate Brody, Ivona T. Olszak, Gregor B. Adams, Urban Ramstedt, Wayne A. Marasco, and David T. Scadden6 July 2004 | Human Gene Therapy, Vol. 10, No. 15Establishment of an optimised gene transfer protocol for human primary T lymphocytes according to clinical requirements6 October 1999 | Gene Therapy, Vol. 6, No. 10Potential use of T cell receptor genes to modify hematopoietic stem cells for the gene therapy of cancerPathology & Oncology Research, Vol. 5, No. 1Inhibition of Human Immunodeficiency Virus Type 1 by Tat/Rev-Regulated Expression of Cytosine Deaminase, Interferon alpha2, or Diphtheria Toxin Compared with Inhibition by Transdominant Rev Jack A. Ragheb, Larry Couture, Craig Mullen, Anthony Ridgway, and Richard A. Morgan6 July 2004 | Human Gene Therapy, Vol. 10, No. 1T Cell Activation Modulates Retrovirus-Mediated Gene Expression E. R. Quinn, L. G. Lum, and K. T. Trevor20 March 2008 | Human Gene Therapy, Vol. 9, No. 10Highly-efficient gene transfer with retroviral vectors into human T lymphocytes on fibronectin25 December 2001 | British Journal of Haematology, Vol. 102, No. 2The Biochemistry of Gene Therapy for AIDS1 June 2005 | cclm, Vol. 36, No. 4Comparative Analyses of Intracellularly Expressed Antisense RNAs as Inhibitors of Human Immunodeficiency Virus Type 1 ReplicationJournal of Virology, Vol. 72, No. 3Reduction in SIV replication in rhesus macaques infused with autologous lymphocytes engineered with antiviral genesNature Medicine, Vol. 4, No. 2The Use of Ribozymes in Gene Therapy Approaches to AIDSExploiting RNAGene Therapy for Infectious DiseasesClinical Microbiology Reviews, Vol. 11, No. 1 Volume 7Issue 10Jul 1996 InformationCopyright 1996, Mary Ann Liebert, Inc.To cite this article:PRINCIPAL INVESTIGATOR Richard A. Morgan and MEDICALLY RESPONSIBLE INVESTIGATOR Robert Walker.Gene Therapy for AIDS Using Retroviral Mediated Gene Transfer to Deliver HIV-1 Antisense TAR and Transdominant Rev Protein Genes to Syngeneic Lymphocytes in HIV-1 Infected Identical Twins. National Institutes of Health, Bethesda, Maryland.Human Gene Therapy.Jul 1996.1281-1306.http://doi.org/10.1089/hum.1996.7.10-1281Published in Volume: 7 Issue 10: March 20, 2008PDF download" @default.
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