FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987173022> ?p ?o ?g. }

• W1987173022 endingPage "1258" @default.
• W1987173022 startingPage "1252" @default.
• W1987173022 abstract "Examining the unresolved relationship between the lower motor neuron disorder progressive muscular atrophy (PMA) and ALS is important in clinical practice because of emerging therapies.Spinal and brainstem tissues donated from patients with ALS/motor neuron disorder (n = 81) were examined. Using retrospective case note review, the authors assigned patients into three categories: PMA (12), PMA progressing to ALS (6), and ALS ab initio (63). Conventional stains for long tract degeneration and immunocytochemistry for ubiquitin and the macrophage marker CD68 were examined.Rapid progression and typical ubiquitinated inclusions in lower motor neurons were present in 77 (95%) of the cases. Immunocytochemistry for CD68 was a more sensitive marker of long tract pathology in comparison with conventional stains. Half of the cases with PMA showed corticospinal tract degeneration by CD68.Patients with PMA frequently have undetected long tract pathology and most have ubiquitinated inclusions typical of ALS. A patient presenting with PMA with rapid clinical evolution likely has the pathology and pathophysiology of ALS whether or not upper motor neuron signs evolve." @default.
• W1987173022 created "2016-06-24" @default.
• W1987173022 creator A5008494200 @default.
• W1987173022 creator A5016175407 @default.
• W1987173022 creator A5017951012 @default.
• W1987173022 creator A5035247509 @default.
• W1987173022 creator A5045021377 @default.
• W1987173022 creator A5057685617 @default.
• W1987173022 creator A5087727224 @default.
• W1987173022 date "2003-04-22" @default.
• W1987173022 modified "2023-10-17" @default.
• W1987173022 title "Corticospinal tract degeneration in the progressive muscular atrophy variant of ALS" @default.
• W1987173022 cites W1511868656 @default.
• W1987173022 cites W1521835682 @default.
• W1987173022 cites W1580098294 @default.
• W1987173022 cites W1968744160 @default.
• W1987173022 cites W1970213156 @default.
• W1987173022 cites W1970998916 @default.
• W1987173022 cites W1972436933 @default.
• W1987173022 cites W1976087144 @default.
• W1987173022 cites W1978322209 @default.
• W1987173022 cites W1978932408 @default.
• W1987173022 cites W1985788233 @default.
• W1987173022 cites W1986123612 @default.
• W1987173022 cites W1996319685 @default.
• W1987173022 cites W1998073360 @default.
• W1987173022 cites W1998970893 @default.
• W1987173022 cites W2002977156 @default.
• W1987173022 cites W2007478642 @default.
• W1987173022 cites W2008481778 @default.
• W1987173022 cites W2026746320 @default.
• W1987173022 cites W2030793256 @default.
• W1987173022 cites W2035678859 @default.
• W1987173022 cites W2043445771 @default.
• W1987173022 cites W2051125808 @default.
• W1987173022 cites W2065754041 @default.
• W1987173022 cites W2071230819 @default.
• W1987173022 cites W2075818287 @default.
• W1987173022 cites W2095362003 @default.
• W1987173022 cites W2134525125 @default.
• W1987173022 doi "https://doi.org/10.1212/01.wnl.0000058901.75728.4e" @default.
• W1987173022 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12707426" @default.
• W1987173022 hasPublicationYear "2003" @default.
• W1987173022 type Work @default.
• W1987173022 sameAs 1987173022 @default.
• W1987173022 citedByCount "266" @default.
• W1987173022 countsByYear W19871730222012 @default.
• W1987173022 countsByYear W19871730222013 @default.
• W1987173022 countsByYear W19871730222014 @default.
• W1987173022 countsByYear W19871730222015 @default.
• W1987173022 countsByYear W19871730222016 @default.
• W1987173022 countsByYear W19871730222017 @default.
• W1987173022 countsByYear W19871730222018 @default.
• W1987173022 countsByYear W19871730222019 @default.
• W1987173022 countsByYear W19871730222020 @default.
• W1987173022 countsByYear W19871730222021 @default.
• W1987173022 countsByYear W19871730222022 @default.
• W1987173022 countsByYear W19871730222023 @default.
• W1987173022 crossrefType "journal-article" @default.
• W1987173022 hasAuthorship W1987173022A5008494200 @default.
• W1987173022 hasAuthorship W1987173022A5016175407 @default.
• W1987173022 hasAuthorship W1987173022A5017951012 @default.
• W1987173022 hasAuthorship W1987173022A5035247509 @default.
• W1987173022 hasAuthorship W1987173022A5045021377 @default.
• W1987173022 hasAuthorship W1987173022A5057685617 @default.
• W1987173022 hasAuthorship W1987173022A5087727224 @default.
• W1987173022 hasConcept C105702510 @default.
• W1987173022 hasConcept C126838900 @default.
• W1987173022 hasConcept C142724271 @default.
• W1987173022 hasConcept C143409427 @default.
• W1987173022 hasConcept C149550507 @default.
• W1987173022 hasConcept C204232928 @default.
• W1987173022 hasConcept C2776460901 @default.
• W1987173022 hasConcept C2776728740 @default.
• W1987173022 hasConcept C2776752467 @default.
• W1987173022 hasConcept C2778558090 @default.
• W1987173022 hasConcept C2778583998 @default.
• W1987173022 hasConcept C2779134260 @default.
• W1987173022 hasConcept C2779354088 @default.
• W1987173022 hasConcept C2779779279 @default.
• W1987173022 hasConcept C2780596555 @default.
• W1987173022 hasConcept C2781172350 @default.
• W1987173022 hasConcept C2781354215 @default.
• W1987173022 hasConcept C35866371 @default.
• W1987173022 hasConcept C71924100 @default.
• W1987173022 hasConceptScore W1987173022C105702510 @default.
• W1987173022 hasConceptScore W1987173022C126838900 @default.
• W1987173022 hasConceptScore W1987173022C142724271 @default.
• W1987173022 hasConceptScore W1987173022C143409427 @default.
• W1987173022 hasConceptScore W1987173022C149550507 @default.
• W1987173022 hasConceptScore W1987173022C204232928 @default.
• W1987173022 hasConceptScore W1987173022C2776460901 @default.
• W1987173022 hasConceptScore W1987173022C2776728740 @default.
• W1987173022 hasConceptScore W1987173022C2776752467 @default.
• W1987173022 hasConceptScore W1987173022C2778558090 @default.
• W1987173022 hasConceptScore W1987173022C2778583998 @default.
• W1987173022 hasConceptScore W1987173022C2779134260 @default.
• W1987173022 hasConceptScore W1987173022C2779354088 @default.

• next