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• W1987202233 endingPage "12" @default.
• W1987202233 startingPage "1" @default.
• W1987202233 abstract "Fertility preservation is an important issue for patients in reproductive age with early stage cervical cancer. In view of recent developments, our purpose was to review and discuss available surgical alternatives. A literature search was conducted using PUBMED, including papers between 1980 and December 2011. In patients with stage IA1 cervical cancer, conization is a valid alternative. Patients with stage IA2-IB1 disease can be conservatively treated by radical trachelectomy. This is as well-established conservative approach and appears to be safe and effective in allowing a high chance of conception. Prematurity is the most serious issue in pregnancies following trachelectomy. Less invasive options such as simple trachelectomy or conization seem to be feasible for stages IA2-IB1, but more and better evidence is needed. Neoadjuvant therapy might allow conservative surgery to be performed also in patients with more extensive lesions. Ovarian transposition is important when adjuvant radiation is needed. In conclusion, available literature shows that there are interesting fertility-sparing treatment alternatives to the “golden standard” for the management of early cervical cancer in young women." @default.
• W1987202233 created "2016-06-24" @default.
• W1987202233 creator A5046780523 @default.
• W1987202233 date "2012-12-18" @default.
• W1987202233 modified "2023-09-29" @default.
• W1987202233 title "Fertility-Preserving Surgery in Patients with Early Stage Cervical Carcinoma" @default.
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• W1987202233 doi "https://doi.org/10.5402/2012/817065" @default.
• W1987202233 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3539444" @default.
• W1987202233 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23320192" @default.
• W1987202233 hasPublicationYear "2012" @default.
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