Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987221920> ?p ?o ?g. }
- W1987221920 endingPage "e0122354" @default.
- W1987221920 startingPage "e0122354" @default.
- W1987221920 abstract "Genotyping studies of Australian Scedosporium isolates have revealed the strong prevalence of a recently described species: Scedosporium aurantiacum. In addition to occurring in the environment, this fungus is also known to colonise the respiratory tracts of cystic fibrosis (CF) patients. A high throughput Phenotype Microarray (PM) analysis using 94 assorted substrates (sugars, amino acids, hexose-acids and carboxylic acids) was carried out for four isolates exhibiting different levels of virulence, determined using a Galleria mellonella infection model. A significant difference was observed in the substrate utilisation patterns of strains displaying differential virulence. For example, certain sugars such as sucrose (saccharose) were utilised only by low virulence strains whereas some sugar derivatives such as D-turanose promoted respiration only in the more virulent strains. Strains with a higher level of virulence also displayed flexibility and metabolic adaptability at two different temperature conditions tested (28 and 37°C). Phenotype microarray data were integrated with the whole-genome sequence data of S. aurantiacum to reconstruct a pathway map for the metabolism of selected substrates to further elucidate differences between the strains." @default.
- W1987221920 created "2016-06-24" @default.
- W1987221920 creator A5023176163 @default.
- W1987221920 creator A5031600826 @default.
- W1987221920 creator A5032002807 @default.
- W1987221920 creator A5044873766 @default.
- W1987221920 creator A5069669892 @default.
- W1987221920 creator A5077820178 @default.
- W1987221920 creator A5081244493 @default.
- W1987221920 date "2015-03-26" @default.
- W1987221920 modified "2023-10-12" @default.
- W1987221920 title "Phenotypic Profiling of Scedosporium aurantiacum, an Opportunistic Pathogen Colonizing Human Lungs" @default.
- W1987221920 cites W1609495085 @default.
- W1987221920 cites W1965568562 @default.
- W1987221920 cites W1979968951 @default.
- W1987221920 cites W1988007120 @default.
- W1987221920 cites W1999950146 @default.
- W1987221920 cites W2002233958 @default.
- W1987221920 cites W2009062449 @default.
- W1987221920 cites W2010324246 @default.
- W1987221920 cites W2013703942 @default.
- W1987221920 cites W2017737411 @default.
- W1987221920 cites W2022692497 @default.
- W1987221920 cites W2031005159 @default.
- W1987221920 cites W2031681107 @default.
- W1987221920 cites W2040233646 @default.
- W1987221920 cites W2040431677 @default.
- W1987221920 cites W2054320069 @default.
- W1987221920 cites W2056705795 @default.
- W1987221920 cites W2073951385 @default.
- W1987221920 cites W2074614011 @default.
- W1987221920 cites W2093476095 @default.
- W1987221920 cites W2102074615 @default.
- W1987221920 cites W2110439135 @default.
- W1987221920 cites W2110523405 @default.
- W1987221920 cites W2112657452 @default.
- W1987221920 cites W2115225257 @default.
- W1987221920 cites W2116875566 @default.
- W1987221920 cites W2120924657 @default.
- W1987221920 cites W2120977684 @default.
- W1987221920 cites W2123618159 @default.
- W1987221920 cites W2128480720 @default.
- W1987221920 cites W2128601422 @default.
- W1987221920 cites W2131567120 @default.
- W1987221920 cites W2132040510 @default.
- W1987221920 cites W2132890231 @default.
- W1987221920 cites W2136334655 @default.
- W1987221920 cites W2137473653 @default.
- W1987221920 cites W2138507077 @default.
- W1987221920 cites W2147745929 @default.
- W1987221920 cites W2149531397 @default.
- W1987221920 cites W2151043417 @default.
- W1987221920 cites W2153584505 @default.
- W1987221920 cites W2158059832 @default.
- W1987221920 cites W2158464667 @default.
- W1987221920 cites W2159367637 @default.
- W1987221920 cites W2161633414 @default.
- W1987221920 cites W2163717305 @default.
- W1987221920 cites W2166336493 @default.
- W1987221920 cites W2792930549 @default.
- W1987221920 cites W4230770774 @default.
- W1987221920 doi "https://doi.org/10.1371/journal.pone.0122354" @default.
- W1987221920 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4374879" @default.
- W1987221920 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25811884" @default.
- W1987221920 hasPublicationYear "2015" @default.
- W1987221920 type Work @default.
- W1987221920 sameAs 1987221920 @default.
- W1987221920 citedByCount "20" @default.
- W1987221920 countsByYear W19872219202015 @default.
- W1987221920 countsByYear W19872219202016 @default.
- W1987221920 countsByYear W19872219202017 @default.
- W1987221920 countsByYear W19872219202018 @default.
- W1987221920 countsByYear W19872219202019 @default.
- W1987221920 countsByYear W19872219202020 @default.
- W1987221920 countsByYear W19872219202021 @default.
- W1987221920 countsByYear W19872219202022 @default.
- W1987221920 crossrefType "journal-article" @default.
- W1987221920 hasAuthorship W1987221920A5023176163 @default.
- W1987221920 hasAuthorship W1987221920A5031600826 @default.
- W1987221920 hasAuthorship W1987221920A5032002807 @default.
- W1987221920 hasAuthorship W1987221920A5044873766 @default.
- W1987221920 hasAuthorship W1987221920A5069669892 @default.
- W1987221920 hasAuthorship W1987221920A5077820178 @default.
- W1987221920 hasAuthorship W1987221920A5081244493 @default.
- W1987221920 hasBestOaLocation W19872219201 @default.
- W1987221920 hasConcept C104317684 @default.
- W1987221920 hasConcept C127716648 @default.
- W1987221920 hasConcept C135763542 @default.
- W1987221920 hasConcept C2779032433 @default.
- W1987221920 hasConcept C54355233 @default.
- W1987221920 hasConcept C60987743 @default.
- W1987221920 hasConcept C77434933 @default.
- W1987221920 hasConcept C86803240 @default.
- W1987221920 hasConcept C89423630 @default.
- W1987221920 hasConceptScore W1987221920C104317684 @default.
- W1987221920 hasConceptScore W1987221920C127716648 @default.
- W1987221920 hasConceptScore W1987221920C135763542 @default.
- W1987221920 hasConceptScore W1987221920C2779032433 @default.