Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987238214> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W1987238214 endingPage "767" @default.
- W1987238214 startingPage "761" @default.
- W1987238214 abstract "Abstract: In slices obtained from the ventral and the dorsal guinea pig spinal cord both forskolin and vasoactive intestinal peptide (VIP) caused a dose-dependent stimulation of the production of cyclic AMP. By contrast capsaicin stimulated cyclic AMP formation only in the dorsal cord; no effect was observed in the ventral cord. The (α2-adrenergic agonist UK-14,304 dose-dependently inhibited the production of cyclic AMP in both the dorsal and ventral aspects of the cord when the formation of cyclic AMP had been stimulated with 3 μM forskolin, the maximal inhibition amounting to 25–32%. Also the basal (i.e., unstimulated) production of cyclic AMP was inhibited, the inhibition amounting to about 16–18%. However, after stimulation of cyclic AMP formation in the dorsal cord with capsaicin, UK-14,304 was virtually ineffective in inhibiting the accumulation of cyclic AMP. Also, when the formation of cyclic AMP was stimulated with VIP, UK-14,304 was virtually ineffective in inhibiting the formation of cyclic AMP both in the ventral and the dorsal parts of the cord. When cyclic AMP production had been stimulated with forskolin the ability of UK-14,304 to inhibit the formation of cyclic AMP was not attenuated by capsaicin, either in the ventral or in the dorsal cord. The results are discussed with the notion that cyclic AMP inhibitory spinal cord α2-adrenoceptors are located on cells accessible to stimulation of cyclic AMP with forskolin but not with capsaicin or VIP." @default.
- W1987238214 created "2016-06-24" @default.
- W1987238214 creator A5000367311 @default.
- W1987238214 creator A5081984122 @default.
- W1987238214 date "1989-03-01" @default.
- W1987238214 modified "2023-09-27" @default.
- W1987238214 title "?<sub>2</sub>-Adrenoceptors Mediate Inhibition of Cyclic AMP Production in the Spinal Cord After Stimulation of Cyclic AMP with Forskolin but Not After Stimulation with Capsaicin or Vasoactive Intestinal Peptide" @default.
- W1987238214 cites W1966025228 @default.
- W1987238214 cites W1982324672 @default.
- W1987238214 cites W1983360652 @default.
- W1987238214 cites W1987346819 @default.
- W1987238214 cites W1990155458 @default.
- W1987238214 cites W1994649547 @default.
- W1987238214 cites W1997997502 @default.
- W1987238214 cites W2003313596 @default.
- W1987238214 cites W2009993667 @default.
- W1987238214 cites W2012326801 @default.
- W1987238214 cites W2021418799 @default.
- W1987238214 cites W2022284378 @default.
- W1987238214 cites W2047693504 @default.
- W1987238214 cites W2049952900 @default.
- W1987238214 cites W2073212068 @default.
- W1987238214 cites W2075351452 @default.
- W1987238214 cites W2081038091 @default.
- W1987238214 cites W2083353593 @default.
- W1987238214 cites W2083610854 @default.
- W1987238214 cites W2086475877 @default.
- W1987238214 cites W2090135185 @default.
- W1987238214 cites W2113079273 @default.
- W1987238214 cites W2134135587 @default.
- W1987238214 cites W2169503005 @default.
- W1987238214 cites W2277063536 @default.
- W1987238214 cites W2419049440 @default.
- W1987238214 cites W4299619783 @default.
- W1987238214 doi "https://doi.org/10.1111/j.1471-4159.1989.tb02520.x" @default.
- W1987238214 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2537376" @default.
- W1987238214 hasPublicationYear "1989" @default.
- W1987238214 type Work @default.
- W1987238214 sameAs 1987238214 @default.
- W1987238214 citedByCount "8" @default.
- W1987238214 crossrefType "journal-article" @default.
- W1987238214 hasAuthorship W1987238214A5000367311 @default.
- W1987238214 hasAuthorship W1987238214A5081984122 @default.
- W1987238214 hasConcept C104317684 @default.
- W1987238214 hasConcept C118303440 @default.
- W1987238214 hasConcept C126322002 @default.
- W1987238214 hasConcept C134018914 @default.
- W1987238214 hasConcept C169760540 @default.
- W1987238214 hasConcept C170493617 @default.
- W1987238214 hasConcept C185592680 @default.
- W1987238214 hasConcept C24998067 @default.
- W1987238214 hasConcept C2778524494 @default.
- W1987238214 hasConcept C2779276759 @default.
- W1987238214 hasConcept C2780051329 @default.
- W1987238214 hasConcept C2780775167 @default.
- W1987238214 hasConcept C512185932 @default.
- W1987238214 hasConcept C55493867 @default.
- W1987238214 hasConcept C71924100 @default.
- W1987238214 hasConcept C8330315 @default.
- W1987238214 hasConcept C86803240 @default.
- W1987238214 hasConceptScore W1987238214C104317684 @default.
- W1987238214 hasConceptScore W1987238214C118303440 @default.
- W1987238214 hasConceptScore W1987238214C126322002 @default.
- W1987238214 hasConceptScore W1987238214C134018914 @default.
- W1987238214 hasConceptScore W1987238214C169760540 @default.
- W1987238214 hasConceptScore W1987238214C170493617 @default.
- W1987238214 hasConceptScore W1987238214C185592680 @default.
- W1987238214 hasConceptScore W1987238214C24998067 @default.
- W1987238214 hasConceptScore W1987238214C2778524494 @default.
- W1987238214 hasConceptScore W1987238214C2779276759 @default.
- W1987238214 hasConceptScore W1987238214C2780051329 @default.
- W1987238214 hasConceptScore W1987238214C2780775167 @default.
- W1987238214 hasConceptScore W1987238214C512185932 @default.
- W1987238214 hasConceptScore W1987238214C55493867 @default.
- W1987238214 hasConceptScore W1987238214C71924100 @default.
- W1987238214 hasConceptScore W1987238214C8330315 @default.
- W1987238214 hasConceptScore W1987238214C86803240 @default.
- W1987238214 hasIssue "3" @default.
- W1987238214 hasLocation W19872382141 @default.
- W1987238214 hasLocation W19872382142 @default.
- W1987238214 hasOpenAccess W1987238214 @default.
- W1987238214 hasPrimaryLocation W19872382141 @default.
- W1987238214 hasRelatedWork W1966638871 @default.
- W1987238214 hasRelatedWork W1975696001 @default.
- W1987238214 hasRelatedWork W1987238214 @default.
- W1987238214 hasRelatedWork W2003450342 @default.
- W1987238214 hasRelatedWork W2016408069 @default.
- W1987238214 hasRelatedWork W2027568289 @default.
- W1987238214 hasRelatedWork W2053936620 @default.
- W1987238214 hasRelatedWork W2070211997 @default.
- W1987238214 hasRelatedWork W2084109973 @default.
- W1987238214 hasRelatedWork W2089805841 @default.
- W1987238214 hasVolume "52" @default.
- W1987238214 isParatext "false" @default.
- W1987238214 isRetracted "false" @default.
- W1987238214 magId "1987238214" @default.
- W1987238214 workType "article" @default.