Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987240108> ?p ?o ?g. }
- W1987240108 endingPage "8" @default.
- W1987240108 startingPage "1" @default.
- W1987240108 abstract "Recently, we reported that a complex with an essential role in the degradation of Fructose-1,6-bisphosphatase in yeast is well conserved in mammalian cells; we named this mammalian complex C-terminal to the Lissencephaly type-1-like homology (CTLH) complex. Although the function of the CTLH complex remains unclear, here we used yeast two-hybrid screening to isolate Hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) as a protein binding to a key component of CTLH complex, Armadillo repeat containing 8 (ARMc8) α. The association was confirmed by a yeast two-hybrid assay and a co-immunoprecipitation assay. The proline-rich domain of HRS was essential for the association. As demonstrated through immunofluorescence microscopy, ARMc8α co-localized with HRS. ARMc8α promoted the interaction of HRS with various ubiquitinated proteins through the ubiquitin-interacting motif. These findings suggest that HRS mediates protein endosomal trafficking partly through its interaction with ARMc8α." @default.
- W1987240108 created "2016-06-24" @default.
- W1987240108 creator A5017323255 @default.
- W1987240108 creator A5023838708 @default.
- W1987240108 creator A5027581145 @default.
- W1987240108 creator A5031542442 @default.
- W1987240108 creator A5033913974 @default.
- W1987240108 creator A5043728876 @default.
- W1987240108 creator A5064136261 @default.
- W1987240108 creator A5071896176 @default.
- W1987240108 creator A5083180133 @default.
- W1987240108 date "2010-01-13" @default.
- W1987240108 modified "2023-09-30" @default.
- W1987240108 title "Armadillo Repeat Containing 8α Binds to HRS and Promotes HRS Interaction with Ubiquitinated Proteins" @default.
- W1987240108 cites W1539881139 @default.
- W1987240108 cites W1772777894 @default.
- W1987240108 cites W1843137073 @default.
- W1987240108 cites W1969309483 @default.
- W1987240108 cites W1973086328 @default.
- W1987240108 cites W1979618971 @default.
- W1987240108 cites W1986108347 @default.
- W1987240108 cites W1987038656 @default.
- W1987240108 cites W1992425154 @default.
- W1987240108 cites W1997170902 @default.
- W1987240108 cites W2032117499 @default.
- W1987240108 cites W2036673687 @default.
- W1987240108 cites W2056026047 @default.
- W1987240108 cites W2058921751 @default.
- W1987240108 cites W2059229484 @default.
- W1987240108 cites W2059928769 @default.
- W1987240108 cites W2060913542 @default.
- W1987240108 cites W2062601645 @default.
- W1987240108 cites W2064733220 @default.
- W1987240108 cites W2085480610 @default.
- W1987240108 cites W2087762539 @default.
- W1987240108 cites W2096330480 @default.
- W1987240108 cites W2099381742 @default.
- W1987240108 cites W2105731567 @default.
- W1987240108 cites W2116117181 @default.
- W1987240108 cites W2120226363 @default.
- W1987240108 cites W2137339435 @default.
- W1987240108 cites W2143255074 @default.
- W1987240108 cites W2146117749 @default.
- W1987240108 cites W2154834069 @default.
- W1987240108 cites W2169875902 @default.
- W1987240108 cites W2172240440 @default.
- W1987240108 doi "https://doi.org/10.2174/1874091x01004010001" @default.
- W1987240108 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2835868" @default.
- W1987240108 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20224683" @default.
- W1987240108 hasPublicationYear "2010" @default.
- W1987240108 type Work @default.
- W1987240108 sameAs 1987240108 @default.
- W1987240108 citedByCount "25" @default.
- W1987240108 countsByYear W19872401082012 @default.
- W1987240108 countsByYear W19872401082013 @default.
- W1987240108 countsByYear W19872401082014 @default.
- W1987240108 countsByYear W19872401082015 @default.
- W1987240108 countsByYear W19872401082016 @default.
- W1987240108 countsByYear W19872401082017 @default.
- W1987240108 countsByYear W19872401082021 @default.
- W1987240108 countsByYear W19872401082022 @default.
- W1987240108 crossrefType "journal-article" @default.
- W1987240108 hasAuthorship W1987240108A5017323255 @default.
- W1987240108 hasAuthorship W1987240108A5023838708 @default.
- W1987240108 hasAuthorship W1987240108A5027581145 @default.
- W1987240108 hasAuthorship W1987240108A5031542442 @default.
- W1987240108 hasAuthorship W1987240108A5033913974 @default.
- W1987240108 hasAuthorship W1987240108A5043728876 @default.
- W1987240108 hasAuthorship W1987240108A5064136261 @default.
- W1987240108 hasAuthorship W1987240108A5071896176 @default.
- W1987240108 hasAuthorship W1987240108A5083180133 @default.
- W1987240108 hasBestOaLocation W19872401081 @default.
- W1987240108 hasConcept C102747710 @default.
- W1987240108 hasConcept C104317684 @default.
- W1987240108 hasConcept C11804247 @default.
- W1987240108 hasConcept C174851938 @default.
- W1987240108 hasConcept C25602115 @default.
- W1987240108 hasConcept C2779222958 @default.
- W1987240108 hasConcept C2780157343 @default.
- W1987240108 hasConcept C51639874 @default.
- W1987240108 hasConcept C55493867 @default.
- W1987240108 hasConcept C71829478 @default.
- W1987240108 hasConcept C79879829 @default.
- W1987240108 hasConcept C86803240 @default.
- W1987240108 hasConcept C95444343 @default.
- W1987240108 hasConcept C9760119 @default.
- W1987240108 hasConceptScore W1987240108C102747710 @default.
- W1987240108 hasConceptScore W1987240108C104317684 @default.
- W1987240108 hasConceptScore W1987240108C11804247 @default.
- W1987240108 hasConceptScore W1987240108C174851938 @default.
- W1987240108 hasConceptScore W1987240108C25602115 @default.
- W1987240108 hasConceptScore W1987240108C2779222958 @default.
- W1987240108 hasConceptScore W1987240108C2780157343 @default.
- W1987240108 hasConceptScore W1987240108C51639874 @default.
- W1987240108 hasConceptScore W1987240108C55493867 @default.
- W1987240108 hasConceptScore W1987240108C71829478 @default.
- W1987240108 hasConceptScore W1987240108C79879829 @default.
- W1987240108 hasConceptScore W1987240108C86803240 @default.