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• W1987246334 abstract "A dynamic field shaping collimation system is evaluated for use in stereotactic radiosurgery of non-spherical lesions. The concept is as follows: (a) use the existing circular collimators to define a cone which encompasses the maximum dimensions of the target volume; (b) position two sets of independent rectangular photon collimators immediately upstream from the circular aperture and allow each collimator to have independent translational and rotational motion in order to define, for each increment of arc, a polygonal field shape having up to four straight and four curved edges which enscribe the beam's eye projection of the target; (c) modify the translational and rotational position of each independent collimator with each change in arc angle to continuously shape the instantaneous field to the target shape. A prototype device has been constructed and uses vane control technology developed in a related research project in electron are therapy. The efficacy of this device is illustrated by dose calculations and measurement based on actual clinical data. Dose volume histograms are used to compare the dose received by three techniques: single isocenter treatment using a single circular aperture, dual isocenter treatment, and single isocenter treatment using dynamically shaped fields. Doses were calculated throughout the brain using a volume grid of 3 mm spacing. Dose volume histograms comparing dose within the target volume and brain volume excluding target volume, as well as computed isodose distributions, demonstrate the possible reduction in normal tissue dose burden while simultaneously preserving dose uniformity throughout the prescribed target volume. This simple four-vane collimation system may provide a viable alternate treatment technique for non-spherical lesions." @default.
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• W1987246334 date "1991-10-01" @default.
• W1987246334 modified "2023-09-26" @default.
• W1987246334 title "Dynamic field shaping to optimize stereotactic radiosurgery" @default.
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• W1987246334 doi "https://doi.org/10.1016/0360-3016(91)90283-a" @default.
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