FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987285412> ?p ?o ?g. }

• W1987285412 endingPage "466" @default.
• W1987285412 startingPage "456" @default.
• W1987285412 abstract "Patients with a spectrum of T-cell, B-cell, and phagocytic disorders were studied to correlate the specific immunodeficiency associated with autoantibody and autoimmune disease. Disorders investigated included X-linked hypo-γ-globulinemia, common variable onset hypo-γ-globulinemia, selective IgA deficiency, cellular immunodeficiency with abnormal immunoglobulin synthesis, Wiskott-Aldrich syndrome, ataxia-telangiectasia, chronic mucocutaneous candidiasis, severe combined immunodeficiency, chronic granulomatous disease, and female carriers of chronic granulomatous disease. Autoantibody was detected in all groups except X-linked hypo-γ-globulinemia. Clinical autoimmune disease was observed in patients with X-linked hypo-γ-globulinemia, common variable onset hypo-γ-globulinemia, selective IgA deficiency, Wiskott-Aldrich syndrome, chronic mucocutaneous candidiasis, chronic granulomatous disease, and female carriers of chronic granulomatous disease. No autoantibodies were found in only one immunodeficiency disorder, X-linked hypo-γ-globulinemia. Partial B-cell dysfunction, T-cell dysfunction, and phagocytic dysfunction predispose to autoantibody formation. Clinical autoimmune disorders were found in all types of immunodeficiency except severe combined immunodeficiency. Alternatively, patients with partial deficiencies of both B- and T-cell immunity may have regulator cell defects of helper versus suppressor cell populations which may result in enhanced autoantibody formation. It is of interest that two of the patients with cellular immunodeficiency and abnormal immunoglobulin synthesis who were initially negative for autoantibodies, developed positive autoantibodies after partial reconstruction of T-cell function following treatment with bovine thymosin fraction 5 and fetal thymus transplantation, suggesting that under certain circumstances, enhanced T-cell function may result in autoantibody formation." @default.
• W1987285412 created "2016-06-24" @default.
• W1987285412 creator A5015921092 @default.
• W1987285412 creator A5027316824 @default.
• W1987285412 creator A5069688312 @default.
• W1987285412 creator A5071926391 @default.
• W1987285412 date "1979-12-01" @default.
• W1987285412 modified "2023-09-24" @default.
• W1987285412 title "The prevalence of autoantibodies in T-cell, B-cell, and phagocytic immunodeficiency disorders" @default.
• W1987285412 cites W1486392189 @default.
• W1987285412 cites W1908808127 @default.
• W1987285412 cites W1977602326 @default.
• W1987285412 cites W1980442376 @default.
• W1987285412 cites W1992890491 @default.
• W1987285412 cites W1994686021 @default.
• W1987285412 cites W1999660707 @default.
• W1987285412 cites W2009083134 @default.
• W1987285412 cites W2015907128 @default.
• W1987285412 cites W2019834042 @default.
• W1987285412 cites W2046591510 @default.
• W1987285412 cites W2047799600 @default.
• W1987285412 cites W2051180788 @default.
• W1987285412 cites W2056163752 @default.
• W1987285412 cites W2058784090 @default.
• W1987285412 cites W2060492828 @default.
• W1987285412 cites W2070403315 @default.
• W1987285412 cites W2079081819 @default.
• W1987285412 cites W2079616501 @default.
• W1987285412 cites W2079665897 @default.
• W1987285412 cites W2129115848 @default.
• W1987285412 cites W2143281058 @default.
• W1987285412 cites W2342123488 @default.
• W1987285412 cites W4295094667 @default.
• W1987285412 doi "https://doi.org/10.1016/0090-1229(79)90098-9" @default.
• W1987285412 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/315850" @default.
• W1987285412 hasPublicationYear "1979" @default.
• W1987285412 type Work @default.
• W1987285412 sameAs 1987285412 @default.
• W1987285412 citedByCount "19" @default.
• W1987285412 countsByYear W19872854122012 @default.
• W1987285412 countsByYear W19872854122015 @default.
• W1987285412 crossrefType "journal-article" @default.
• W1987285412 hasAuthorship W1987285412A5015921092 @default.
• W1987285412 hasAuthorship W1987285412A5027316824 @default.
• W1987285412 hasAuthorship W1987285412A5069688312 @default.
• W1987285412 hasAuthorship W1987285412A5071926391 @default.
• W1987285412 hasConcept C104317684 @default.
• W1987285412 hasConcept C142724271 @default.
• W1987285412 hasConcept C156662089 @default.
• W1987285412 hasConcept C159654299 @default.
• W1987285412 hasConcept C163764329 @default.
• W1987285412 hasConcept C203014093 @default.
• W1987285412 hasConcept C2776422140 @default.
• W1987285412 hasConcept C2776433325 @default.
• W1987285412 hasConcept C2777607303 @default.
• W1987285412 hasConcept C2778153459 @default.
• W1987285412 hasConcept C2779019163 @default.
• W1987285412 hasConcept C2779134260 @default.
• W1987285412 hasConcept C2780130043 @default.
• W1987285412 hasConcept C55493867 @default.
• W1987285412 hasConcept C71924100 @default.
• W1987285412 hasConcept C86803240 @default.
• W1987285412 hasConcept C8891405 @default.
• W1987285412 hasConceptScore W1987285412C104317684 @default.
• W1987285412 hasConceptScore W1987285412C142724271 @default.
• W1987285412 hasConceptScore W1987285412C156662089 @default.
• W1987285412 hasConceptScore W1987285412C159654299 @default.
• W1987285412 hasConceptScore W1987285412C163764329 @default.
• W1987285412 hasConceptScore W1987285412C203014093 @default.
• W1987285412 hasConceptScore W1987285412C2776422140 @default.
• W1987285412 hasConceptScore W1987285412C2776433325 @default.
• W1987285412 hasConceptScore W1987285412C2777607303 @default.
• W1987285412 hasConceptScore W1987285412C2778153459 @default.
• W1987285412 hasConceptScore W1987285412C2779019163 @default.
• W1987285412 hasConceptScore W1987285412C2779134260 @default.
• W1987285412 hasConceptScore W1987285412C2780130043 @default.
• W1987285412 hasConceptScore W1987285412C55493867 @default.
• W1987285412 hasConceptScore W1987285412C71924100 @default.
• W1987285412 hasConceptScore W1987285412C86803240 @default.
• W1987285412 hasConceptScore W1987285412C8891405 @default.
• W1987285412 hasIssue "4" @default.
• W1987285412 hasLocation W19872854121 @default.
• W1987285412 hasLocation W19872854122 @default.
• W1987285412 hasOpenAccess W1987285412 @default.
• W1987285412 hasPrimaryLocation W19872854121 @default.
• W1987285412 hasRelatedWork W1569247537 @default.
• W1987285412 hasRelatedWork W1586923479 @default.
• W1987285412 hasRelatedWork W1987285412 @default.
• W1987285412 hasRelatedWork W2084801194 @default.
• W1987285412 hasRelatedWork W2334934116 @default.
• W1987285412 hasRelatedWork W2507138213 @default.
• W1987285412 hasRelatedWork W2807317117 @default.
• W1987285412 hasRelatedWork W2964243114 @default.
• W1987285412 hasRelatedWork W3205938183 @default.
• W1987285412 hasRelatedWork W2264373215 @default.
• W1987285412 hasVolume "14" @default.
• W1987285412 isParatext "false" @default.
• W1987285412 isRetracted "false" @default.

• next