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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987299404> ?p ?o ?g. }

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• W1987299404 abstract "Research on atrophic rhinitis of pigs has shown that both Bordetella bronchiseptica infection and experimental treatment with acetic acid predispose the nasal mucosa to colonization with Pasteurella multocida. Gnotobiotic piglets aged 3 days were dosed intranasally with either B. bronchiseptica, (n=6) or acetic acid 1 per cent, (n= 10) and killed at intervals up to the 4th day after treatment. Samples of the ventral turbinates were examined by light microscopy and scanning and transmission electron microscopy. Within 12 h acetic acid induced loss of cilia, oedema, focal cell exfoliations, mitochondrial swelling and inflammatory cell infiltration. Bordetella bronchiseptica induced only a limited oedema and loss of cilia. Colonization of cilia by the bacteria was observed 96 h after infection. We conclude that, although acetic acid and B. bronchiseptica do not induce the same modifications of the nasal respiratory epithelium, their action causes stagnation of nasal mucus, which results in a nasal environment favourable to colonization by Pasteurella multocida." @default.
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• W1987299404 date "1993-07-01" @default.
• W1987299404 modified "2023-10-01" @default.
• W1987299404 title "Nasal epithelial changes induced in piglets by acetic acid and by Bordetella bronchiseptica" @default.
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• W1987299404 doi "https://doi.org/10.1016/s0021-9975(08)80241-1" @default.
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