Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987316597> ?p ?o ?g. }
- W1987316597 endingPage "551e" @default.
- W1987316597 startingPage "543e" @default.
- W1987316597 abstract "Background: Vascularized composite allotransplants consist of heterogeneous tissues from different germ layers, which include skin, muscle, bone, fat, nerves, and lymph nodes. The antigenic diversity of these tissues, particularly of the highly immunogenic skin component, necessitates potent immunosuppressive regimens similar to that of some solid organ transplants. Indeed, the lifelong, high-dose, multidrug immunosuppressive protocols expose vascularized composite allotransplant recipients to considerable risk of infectious, metabolic, and neoplastic sequelae. In this article, the authors review the infectious risk to patients after vascularized composite allotransplantation, with special attention to the somewhat limited experience with the prophylaxis and treatment of infections after this innovative reconstructive surgery. Methods: A review of the literature was undertaken to elucidate the characterization, prophylaxis, and treatment of all documented infectious complications. Results: Infections in face and hand vascularized composite allotransplants follow a course similar to that of solid organ transplants. Several differences exist, including the unique flora of craniomaxillofacial transplants, the increased risk of donor-derived infections, and the alteration of the risk-to-benefit ratio for cytomegalovirus infections. Conclusions: The patient with a face or limb transplant has many of the same infectious risks as a lung transplant recipient, which include bacterial, viral, and fungal infections. Because of the anatomy, mucosal exposure, and differing donor flora, however, the face or limb transplant is susceptible to invasive diseases from a variety of microbes." @default.
- W1987316597 created "2016-06-24" @default.
- W1987316597 creator A5005410152 @default.
- W1987316597 creator A5022806526 @default.
- W1987316597 creator A5038737997 @default.
- W1987316597 creator A5038988386 @default.
- W1987316597 creator A5062222528 @default.
- W1987316597 creator A5064735252 @default.
- W1987316597 creator A5065121361 @default.
- W1987316597 creator A5074805124 @default.
- W1987316597 creator A5085923859 @default.
- W1987316597 date "2014-04-01" @default.
- W1987316597 modified "2023-10-16" @default.
- W1987316597 title "Characterization, Prophylaxis, and Treatment of Infectious Complications in Craniomaxillofacial and Upper Extremity Allotransplantation" @default.
- W1987316597 cites W1580373248 @default.
- W1987316597 cites W1862806668 @default.
- W1987316597 cites W1964060607 @default.
- W1987316597 cites W1966300467 @default.
- W1987316597 cites W1975294422 @default.
- W1987316597 cites W1976118007 @default.
- W1987316597 cites W1981631137 @default.
- W1987316597 cites W1985528308 @default.
- W1987316597 cites W1986082039 @default.
- W1987316597 cites W1990118856 @default.
- W1987316597 cites W1997060234 @default.
- W1987316597 cites W2000432729 @default.
- W1987316597 cites W2001534056 @default.
- W1987316597 cites W2023676063 @default.
- W1987316597 cites W2025792690 @default.
- W1987316597 cites W2026145100 @default.
- W1987316597 cites W2027923435 @default.
- W1987316597 cites W2029001956 @default.
- W1987316597 cites W2031660885 @default.
- W1987316597 cites W2031832264 @default.
- W1987316597 cites W2038485278 @default.
- W1987316597 cites W2039603262 @default.
- W1987316597 cites W2052719306 @default.
- W1987316597 cites W2055115673 @default.
- W1987316597 cites W2056297349 @default.
- W1987316597 cites W2057481423 @default.
- W1987316597 cites W2066378742 @default.
- W1987316597 cites W2066830805 @default.
- W1987316597 cites W2068604359 @default.
- W1987316597 cites W2072448872 @default.
- W1987316597 cites W2077751121 @default.
- W1987316597 cites W2078261694 @default.
- W1987316597 cites W2079452465 @default.
- W1987316597 cites W2083174265 @default.
- W1987316597 cites W2089324618 @default.
- W1987316597 cites W2090510000 @default.
- W1987316597 cites W2098100304 @default.
- W1987316597 cites W2098431932 @default.
- W1987316597 cites W2098535419 @default.
- W1987316597 cites W2099678451 @default.
- W1987316597 cites W2100835692 @default.
- W1987316597 cites W2106759581 @default.
- W1987316597 cites W2120252347 @default.
- W1987316597 cites W2122478002 @default.
- W1987316597 cites W2130835454 @default.
- W1987316597 cites W2144606768 @default.
- W1987316597 cites W2145677626 @default.
- W1987316597 cites W2149079038 @default.
- W1987316597 cites W2150900225 @default.
- W1987316597 cites W2151519246 @default.
- W1987316597 cites W2157955110 @default.
- W1987316597 cites W2313721424 @default.
- W1987316597 cites W2332401864 @default.
- W1987316597 cites W4238234042 @default.
- W1987316597 cites W4250587277 @default.
- W1987316597 cites W4294349031 @default.
- W1987316597 doi "https://doi.org/10.1097/prs.0000000000000015" @default.
- W1987316597 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24675206" @default.
- W1987316597 hasPublicationYear "2014" @default.
- W1987316597 type Work @default.
- W1987316597 sameAs 1987316597 @default.
- W1987316597 citedByCount "31" @default.
- W1987316597 countsByYear W19873165972014 @default.
- W1987316597 countsByYear W19873165972015 @default.
- W1987316597 countsByYear W19873165972016 @default.
- W1987316597 countsByYear W19873165972017 @default.
- W1987316597 countsByYear W19873165972018 @default.
- W1987316597 countsByYear W19873165972019 @default.
- W1987316597 countsByYear W19873165972020 @default.
- W1987316597 countsByYear W19873165972021 @default.
- W1987316597 countsByYear W19873165972022 @default.
- W1987316597 countsByYear W19873165972023 @default.
- W1987316597 crossrefType "journal-article" @default.
- W1987316597 hasAuthorship W1987316597A5005410152 @default.
- W1987316597 hasAuthorship W1987316597A5022806526 @default.
- W1987316597 hasAuthorship W1987316597A5038737997 @default.
- W1987316597 hasAuthorship W1987316597A5038988386 @default.
- W1987316597 hasAuthorship W1987316597A5062222528 @default.
- W1987316597 hasAuthorship W1987316597A5064735252 @default.
- W1987316597 hasAuthorship W1987316597A5065121361 @default.
- W1987316597 hasAuthorship W1987316597A5074805124 @default.
- W1987316597 hasAuthorship W1987316597A5085923859 @default.
- W1987316597 hasConcept C141071460 @default.
- W1987316597 hasConcept C177713679 @default.