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• W1987353048 endingPage "1108" @default.
• W1987353048 startingPage "1103" @default.
• W1987353048 abstract "Plasma cells are cellular factories devoted entirely to the manufacture and export of a single product: soluble immunoglobulin (Ig). As the final mediators of a humoral response, plasma cells play a critical role in adaptive immunity. Although intense effort has been devoted to studying the regulation and requirements for early B cell development, little information has been available on plasma cells. However, more recent work-including studies on genetically altered mice and data from microarray analyses-has begun to identify the regulatory cascades that initiate and maintain the plasma cell phenotype. This review will summarize our current understanding of the molecules that regulate commitment to a plasma cell fate and those that mediate plasma cell function." @default.
• W1987353048 created "2016-06-24" @default.
• W1987353048 creator A5005637454 @default.
• W1987353048 date "2001-12-01" @default.
• W1987353048 modified "2023-10-06" @default.
• W1987353048 title "Plasma cells: finding new light at the end of B cell development" @default.
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• W1987353048 doi "https://doi.org/10.1038/ni1201-1103" @default.
• W1987353048 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11725300" @default.
• W1987353048 hasPublicationYear "2001" @default.
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