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- W1987375545 abstract "Background The total rate of thrombotic complications caused by tunneled central lines (TCL) is still not known, as are the long-term consequences. Aim of the Study Estimation of a rate of thrombotic complications in children with TCL and malignancy and Doppler ultrasound assessment of blood flow after TCL removal. Materials and Methods One hundred twenty-four children were enrolled for the study. Heparin lock was used as a prophylaxis for line occlusion. The rate and type of thrombotic events associated with TCL were analyzed in all patients. In children without an earlier history of thrombosis, a Doppler ultrasound examination was carried out after TCL removal. Results In 45.2% of patients at least 1 thrombotic event occurred. These events were TCL lumen thrombosis (42.8% of patients) and subclavian vein thrombosis (2.4% of patients). In 37 patients Doppler ultrasound was carried out and revealed an abnormal blood flow in the vein that was examined in 59.5% of them. Conclusions The total rate of thrombotic complications in children with TCL and malignancy is high. A substantial proportion of thrombotic complications can be clinically silent. The use of a heparin lock once a week seems far from effective in preventing thrombotic events in patients with TCL. The TCL life span has no influence on the rate of thrombotic events." @default.
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- W1987375545 date "2010-03-01" @default.
- W1987375545 modified "2023-10-16" @default.
- W1987375545 title "Thrombotic Complications of Tunneled Central Lines in Children With Malignancy" @default.
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- W1987375545 doi "https://doi.org/10.1097/mph.0b013e3181c09b0c" @default.
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