FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987378051> ?p ?o ?g. }

• W1987378051 endingPage "e94845" @default.
• W1987378051 startingPage "e94845" @default.
• W1987378051 abstract "Objective The aim of the study was to assess the relationship between insulin-like growth factor I (IGF-I) serum levels and acute ischemic stroke (AIS) in a Chinese population. Methods All consecutive patients with first-ever AIS from August 1, 2011 to July 31, 2013 were recruited to participate in the study. The control group comprised 200 subjects matched for age, gender, and conventional vascular risk factors. IGF-I serum levels were determined by chemiluminescence immunoassay. The National Institutes of Health Stroke Scale (NIHSS) score was assessed on admission blinded to serum IGF-I levels. Results The median serum IGF-1 levels were significantly (P = 0.011) lower in AIS patients (129; IQR, 109–153 ng/mL) compared with control cases (140; IQR, 125–159 ng/mL). We found that an increased risk of AIS was associated with IGF-I levels ≤135 ng/mL (unadjusted OR: 4.17; 95% CI: 2.52–6.89; P = 0.000). This relationship was confirmed in the dose-response model. In multivariate analysis, there was still an increased risk of AIS associated with IGF-I levels ≤135 ng/mL (OR: 2.16; 95% CI:1.33–3.52; P = 0.002) after adjusting for possible confounders. Conclusion Lower IGF-I levels are significantly related to risk of stroke, independent from other traditional and emerging risk factors, suggesting that they may play a role in the pathogenesis of AIS. Thus, strokes were more likely to occur in patients with low serum IGF-I levels in the Chinese population; further, post-ischemic IGF-I therapy may be beneficial for stroke." @default.
• W1987378051 created "2016-06-24" @default.
• W1987378051 creator A5011336486 @default.
• W1987378051 creator A5014163880 @default.
• W1987378051 creator A5021281009 @default.
• W1987378051 creator A5030333910 @default.
• W1987378051 creator A5043099587 @default.
• W1987378051 date "2014-04-11" @default.
• W1987378051 modified "2023-09-24" @default.
• W1987378051 title "The Relationship between Serum Insulin-Like Growth Factor I Levels and Ischemic Stroke Risk" @default.
• W1987378051 cites W1543788907 @default.
• W1987378051 cites W1972020024 @default.
• W1987378051 cites W1972763246 @default.
• W1987378051 cites W1982853378 @default.
• W1987378051 cites W1997329894 @default.
• W1987378051 cites W2011449660 @default.
• W1987378051 cites W2012837633 @default.
• W1987378051 cites W2014035493 @default.
• W1987378051 cites W2018172813 @default.
• W1987378051 cites W2020947579 @default.
• W1987378051 cites W2023925005 @default.
• W1987378051 cites W2032279605 @default.
• W1987378051 cites W2041584707 @default.
• W1987378051 cites W2045600960 @default.
• W1987378051 cites W2050963407 @default.
• W1987378051 cites W2053571606 @default.
• W1987378051 cites W2055123759 @default.
• W1987378051 cites W2056598999 @default.
• W1987378051 cites W2057418848 @default.
• W1987378051 cites W2058868308 @default.
• W1987378051 cites W2060649371 @default.
• W1987378051 cites W2066490129 @default.
• W1987378051 cites W2067395123 @default.
• W1987378051 cites W2074596771 @default.
• W1987378051 cites W2077548365 @default.
• W1987378051 cites W2078103827 @default.
• W1987378051 cites W2080504768 @default.
• W1987378051 cites W2081404489 @default.
• W1987378051 cites W2081750181 @default.
• W1987378051 cites W2107327751 @default.
• W1987378051 cites W2117698153 @default.
• W1987378051 cites W2119442234 @default.
• W1987378051 cites W2126706827 @default.
• W1987378051 cites W2127984332 @default.
• W1987378051 cites W2128667978 @default.
• W1987378051 cites W2131327815 @default.
• W1987378051 cites W2138595885 @default.
• W1987378051 cites W2141177022 @default.
• W1987378051 cites W2141842749 @default.
• W1987378051 cites W2145397058 @default.
• W1987378051 cites W2151076854 @default.
• W1987378051 cites W2151463155 @default.
• W1987378051 cites W2155645904 @default.
• W1987378051 cites W2166163560 @default.
• W1987378051 doi "https://doi.org/10.1371/journal.pone.0094845" @default.
• W1987378051 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3984250" @default.
• W1987378051 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24728374" @default.
• W1987378051 hasPublicationYear "2014" @default.
• W1987378051 type Work @default.
• W1987378051 sameAs 1987378051 @default.
• W1987378051 citedByCount "33" @default.
• W1987378051 countsByYear W19873780512014 @default.
• W1987378051 countsByYear W19873780512015 @default.
• W1987378051 countsByYear W19873780512016 @default.
• W1987378051 countsByYear W19873780512018 @default.
• W1987378051 countsByYear W19873780512019 @default.
• W1987378051 countsByYear W19873780512020 @default.
• W1987378051 countsByYear W19873780512021 @default.
• W1987378051 countsByYear W19873780512022 @default.
• W1987378051 countsByYear W19873780512023 @default.
• W1987378051 crossrefType "journal-article" @default.
• W1987378051 hasAuthorship W1987378051A5011336486 @default.
• W1987378051 hasAuthorship W1987378051A5014163880 @default.
• W1987378051 hasAuthorship W1987378051A5021281009 @default.
• W1987378051 hasAuthorship W1987378051A5030333910 @default.
• W1987378051 hasAuthorship W1987378051A5043099587 @default.
• W1987378051 hasBestOaLocation W19873780511 @default.
• W1987378051 hasConcept C126322002 @default.
• W1987378051 hasConcept C127413603 @default.
• W1987378051 hasConcept C134018914 @default.
• W1987378051 hasConcept C146304588 @default.
• W1987378051 hasConcept C170493617 @default.
• W1987378051 hasConcept C2775960820 @default.
• W1987378051 hasConcept C2780645631 @default.
• W1987378051 hasConcept C2780689927 @default.
• W1987378051 hasConcept C2780942790 @default.
• W1987378051 hasConcept C2908647359 @default.
• W1987378051 hasConcept C3020199598 @default.
• W1987378051 hasConcept C50440223 @default.
• W1987378051 hasConcept C541997718 @default.
• W1987378051 hasConcept C555293320 @default.
• W1987378051 hasConcept C71924100 @default.
• W1987378051 hasConcept C77350462 @default.
• W1987378051 hasConcept C78519656 @default.
• W1987378051 hasConcept C90924648 @default.
• W1987378051 hasConcept C99454951 @default.
• W1987378051 hasConceptScore W1987378051C126322002 @default.
• W1987378051 hasConceptScore W1987378051C127413603 @default.

• next