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- W1987381568 abstract "The ability of human peripheral blood lymphocytes to kill antibody-coated Chang liver cells in antibody-dependent cell-mediated cytotoxicity (ADCC) can be blocked with aggregated IgG (agg-IgG) or by soluble immune complexes. Dissociation of aggregates of IgG or immune complexes from the cell surface, however, resulted in partial recovery of the ability both to bind agg-IgG and to kill in the ADCC assay. Our results indicate that “unblocking” of effector cells could occur in vivo when the concentration of circulating immune complexes is lowered." @default.
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- W1987381568 date "1977-05-01" @default.
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- W1987381568 title "Reversible blocking of antibody-dependent cell-mediated cytotoxicity" @default.
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- W1987381568 doi "https://doi.org/10.1016/0008-8749(77)90078-8" @default.
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