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- W1987402233 abstract "Abstract Group sequential methods for a two-treatment clinical trial with normal responses are discussed. First we consider the case where the sample sizes for two treatments are possibly unequal between the treatments due to an unequal randomization. Then we discuss group sequential design in the context of a historical control study, that is, under the partial sequential sampling scheme, in which the samples on one treatment, say control, are available at the outset, and the samples on the other treatment, say experimental, are obtained in the group sequential way. We discuss the cases of known and unknown variance for both unbalanced and partial group sequential setups. All of the procedures are discussed with numerical studies." @default.
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- W1987402233 date "2014-01-02" @default.
- W1987402233 modified "2023-09-25" @default.
- W1987402233 title "Unbalanced and Partial Group Sequential Methods for Normal Responses in Clinical Trials" @default.
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- W1987402233 doi "https://doi.org/10.1080/07474946.2014.856618" @default.
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