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- W1987413868 abstract "Although it has been assumed that estrogenic treatment of the skin changes its collagen and moisture content, our experiments indicated that neither topical administration of estrogens (estradiol-17βorhexestrol) in large doses to the skin sample site nor subcutaneous injections in a wide range of doses for 3-week periods altered: 1) collagen, as measured by hydroxyproline; 2) hexosamine; 3) total nitrogen; 4) moisture content in the skin of castrated rats. The action of estradiol-17β, in a wide range of doses (0.01–5.0 μg/day/21 days), upon the above components, plus the effect of the estrogen on the noncollagen protein in the uterus and vagina of the castrate rat, was also studied. Castrate animals which did not receive the estrogen served as controls. The results were expressed in terms of: 1) the concentration (μM/g of dry tissue) and 2) the total amount in the organ (μM/total dry organ). The collagen and noncollagen protein were compared on the basis of dry weight in mg. Analysis of our findings with ..." @default.
- W1987413868 created "2016-06-24" @default.
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- W1987413868 date "1963-07-01" @default.
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- W1987413868 title "A Study of Estrogenic Action on the Collagen, Hexosamine and Nitrogen Content of Skin, Uterus and Vagina" @default.
- W1987413868 doi "https://doi.org/10.1210/endo-73-1-11" @default.
- W1987413868 hasPublicationYear "1963" @default.
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