FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987441363> ?p ?o ?g. }

• W1987441363 endingPage "e109" @default.
• W1987441363 startingPage "e101" @default.
• W1987441363 abstract "ObjectivesTo evaluate risk factors, diagnostic procedures, and treatment outcomes of invasive aspergillosis (IA) in patients with hematological malignancies.MethodsA retrospective analysis of data from proven/probable IA cases that occurred from 2005 to 2009 at 10 hematology centers was performed.ResultsWe identified 176 IA cases that mainly occurred in patients with acute leukemias (58.5%), mostly those on induction/re-induction treatments (39.8%). Prolonged neutropenia was the most frequent risk factor for IA (61.4%). The lungs were the most frequently affected site (93.8%) and computed tomography detected abnormalities in all episodes; however, only 53.7% of patients had findings suggestive of IA. Galactomannan (GM) detection in serum or bronchoalveolar lavage fluid (positive in 79.1% and 78.8% of episodes, respectively) played a crucial role in IA diagnosis. Neutrophil count and antifungal prophylaxis did not influence the GM positivity rate, but empirical therapy decreased this rate (in serum). Of the IA cases, 53.2% responded to initial antifungal therapy. The combination of voriconazole and echinocandin, even as initial or salvage therapy, did not perform better than voriconazole monotherapy (p = 0.924 for initial therapy and p = 0.205 for salvage therapy). Neutrophil recovery had a significant role in the response to initial (but not salvage) antifungal therapy.ConclusionsOur retrospective analysis identified key diagnostic and treatment characteristics, and this understanding could improve the management of hematological malignancy patients with IA." @default.
• W1987441363 created "2016-06-24" @default.
• W1987441363 creator A5001255563 @default.
• W1987441363 creator A5003395249 @default.
• W1987441363 creator A5011721730 @default.
• W1987441363 creator A5013946712 @default.
• W1987441363 creator A5028558550 @default.
• W1987441363 creator A5029056253 @default.
• W1987441363 creator A5036912140 @default.
• W1987441363 creator A5038719530 @default.
• W1987441363 creator A5040533888 @default.
• W1987441363 creator A5041052403 @default.
• W1987441363 creator A5042403652 @default.
• W1987441363 creator A5045455980 @default.
• W1987441363 creator A5054654885 @default.
• W1987441363 creator A5055053269 @default.
• W1987441363 creator A5059315641 @default.
• W1987441363 creator A5060929703 @default.
• W1987441363 creator A5080350639 @default.
• W1987441363 creator A5083291598 @default.
• W1987441363 creator A5084353373 @default.
• W1987441363 creator A5084596816 @default.
• W1987441363 creator A5086152940 @default.
• W1987441363 date "2013-02-01" @default.
• W1987441363 modified "2023-10-17" @default.
• W1987441363 title "Invasive aspergillosis in patients with hematological malignancies in the Czech and Slovak republics: Fungal InfectioN Database (FIND) analysis, 2005–2009" @default.
• W1987441363 cites W1819112229 @default.
• W1987441363 cites W1828625180 @default.
• W1987441363 cites W1954433860 @default.
• W1987441363 cites W1970921535 @default.
• W1987441363 cites W1984461782 @default.
• W1987441363 cites W1994312167 @default.
• W1987441363 cites W2000059657 @default.
• W1987441363 cites W2001579789 @default.
• W1987441363 cites W2021836997 @default.
• W1987441363 cites W2024053606 @default.
• W1987441363 cites W2050427285 @default.
• W1987441363 cites W2073437339 @default.
• W1987441363 cites W2078377705 @default.
• W1987441363 cites W2082695689 @default.
• W1987441363 cites W2098918954 @default.
• W1987441363 cites W2107040094 @default.
• W1987441363 cites W2108627308 @default.
• W1987441363 cites W2109374935 @default.
• W1987441363 cites W2109814431 @default.
• W1987441363 cites W2111240524 @default.
• W1987441363 cites W2123114992 @default.
• W1987441363 cites W2129942501 @default.
• W1987441363 cites W2131100764 @default.
• W1987441363 cites W2133167433 @default.
• W1987441363 cites W2133328722 @default.
• W1987441363 cites W2141436450 @default.
• W1987441363 cites W2142482664 @default.
• W1987441363 cites W2144686332 @default.
• W1987441363 cites W2151209623 @default.
• W1987441363 cites W2151939809 @default.
• W1987441363 cites W2163712787 @default.
• W1987441363 cites W2166734004 @default.
• W1987441363 cites W2166836952 @default.
• W1987441363 cites W3025952528 @default.
• W1987441363 doi "https://doi.org/10.1016/j.ijid.2012.09.004" @default.
• W1987441363 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23084969" @default.
• W1987441363 hasPublicationYear "2013" @default.
• W1987441363 type Work @default.
• W1987441363 sameAs 1987441363 @default.
• W1987441363 citedByCount "19" @default.
• W1987441363 countsByYear W19874413632013 @default.
• W1987441363 countsByYear W19874413632014 @default.
• W1987441363 countsByYear W19874413632015 @default.
• W1987441363 countsByYear W19874413632016 @default.
• W1987441363 countsByYear W19874413632017 @default.
• W1987441363 countsByYear W19874413632018 @default.
• W1987441363 countsByYear W19874413632019 @default.
• W1987441363 countsByYear W19874413632020 @default.
• W1987441363 countsByYear W19874413632021 @default.
• W1987441363 countsByYear W19874413632022 @default.
• W1987441363 crossrefType "journal-article" @default.
• W1987441363 hasAuthorship W1987441363A5001255563 @default.
• W1987441363 hasAuthorship W1987441363A5003395249 @default.
• W1987441363 hasAuthorship W1987441363A5011721730 @default.
• W1987441363 hasAuthorship W1987441363A5013946712 @default.
• W1987441363 hasAuthorship W1987441363A5028558550 @default.
• W1987441363 hasAuthorship W1987441363A5029056253 @default.
• W1987441363 hasAuthorship W1987441363A5036912140 @default.
• W1987441363 hasAuthorship W1987441363A5038719530 @default.
• W1987441363 hasAuthorship W1987441363A5040533888 @default.
• W1987441363 hasAuthorship W1987441363A5041052403 @default.
• W1987441363 hasAuthorship W1987441363A5042403652 @default.
• W1987441363 hasAuthorship W1987441363A5045455980 @default.
• W1987441363 hasAuthorship W1987441363A5054654885 @default.
• W1987441363 hasAuthorship W1987441363A5055053269 @default.
• W1987441363 hasAuthorship W1987441363A5059315641 @default.
• W1987441363 hasAuthorship W1987441363A5060929703 @default.
• W1987441363 hasAuthorship W1987441363A5080350639 @default.
• W1987441363 hasAuthorship W1987441363A5083291598 @default.
• W1987441363 hasAuthorship W1987441363A5084353373 @default.
• W1987441363 hasAuthorship W1987441363A5084596816 @default.
• W1987441363 hasAuthorship W1987441363A5086152940 @default.

• next