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- W1987455335 abstract "Bipolar electrode (BPE) focusing locally enriches charged analytes in a microchannel along an electric field gradient that opposes a counter-flow. This electric field gradient forms at the boundary of an ion depletion zone generated by the BPE. Here, we demonstrate concentration enrichment of a fluorescent tracer by up to 500 000-fold. The use of a dual-channel microfluidic configuration, composed of two microchannels electrochemically connected by a BPE, enhances the rate of enrichment (up to 71-fold/s). Faradaic reactions at the ends of the BPE generate ion depletion and enrichment zones in the two, separated channels. This type of device is equivalent to previously reported micro/nanochannel junction arrangements used for ion concentration polarization, but it is experimentally more flexible and much simpler to construct." @default.
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- W1987455335 date "2011-02-25" @default.
- W1987455335 modified "2023-10-04" @default.
- W1987455335 title "Bipolar Electrode Focusing: Faradaic Ion Concentration Polarization" @default.
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- W1987455335 doi "https://doi.org/10.1021/ac103302j" @default.
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