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• W1987458345 abstract "The TRAMP complex assists the nuclear exosome to degrade a broad range of ribonucleic acid (RNA) substrates by increasing both exoribonucleolytic activity and substrate specificity. However, how the interactions between the TRAMP subunits and the components of the nuclear exosome regulate their functions in RNA degradation and substrate specificity remain unclear. This review aims to provide a summary of the recent findings on the role of the TRAMP complex in nuclear RNA degradation. The new insights from recent structural biological studies are discussed." @default.
• W1987458345 created "2016-06-24" @default.
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• W1987458345 date "2015-04-01" @default.
• W1987458345 modified "2023-10-01" @default.
• W1987458345 title "Current perspectives on the role of TRAMP in nuclear RNA surveillance and quality control" @default.
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• W1987458345 doi "https://doi.org/10.2147/rrbc.s58509" @default.
• W1987458345 hasPublicationYear "2015" @default.
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