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• W1987478547 abstract "<h3>Background</h3> The Freestyle stentless aortic root bioprosthesis has excellent hemodynamics and durability through 10 years. The purpose of this report is to present clinical outcomes in a large multicenter cohort through 15 years. <h3>Methods</h3> The multicenter evaluation of the Freestyle valve began in 1992 at 21 centers in North America and Europe. In 1997, a long-term study continued, including 725 patients from 8 of the original centers; clinical outcomes data after 10 years have continued to be collected at 6 of 8 centers. <h3>Results</h3> Patient age was 71.7 ± 7.9 years. There were 402 (55.4%) men and 323 (44.6%) women. Total follow-up was 5,491.2 patient-years. There were 52 late reoperations, with explant of the bioprosthesis in 47 cases. Respective 10- and 15-year survival was 46.2% ± 2.3% and 25.9% ± 3.2%; freedom from valve-related death was 94.9% ± 1.5% and 92.7% ± 3.5%; freedom from reoperation was 92.3% ± 1.8% and 80.7% ± 5.0%; and freedom from explant owing to structural valve deterioration was 96.5% ± 1.3% and 83.3% ± 4.8%. Increased age was associated with higher risks of all-cause mortality and valve-related mortality and lower risks of reoperation and explant caused by structural valve deterioration. <h3>Conclusions</h3> In this long-term, multicenter, observational study, the Freestyle stentless aortic root bioprosthesis offered good clinical outcomes in terms of survival, freedom from valve-related mortality, freedom from reoperation, and freedom from structural valve deterioration. The Freestyle valve is a viable option for use in patients undergoing bioprosthetic aortic valve replacement and for anticipated desire for long-term durability." @default.
• W1987478547 created "2016-06-24" @default.
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• W1987478547 date "2014-02-01" @default.
• W1987478547 modified "2023-10-17" @default.
• W1987478547 title "Long-Term Clinical Outcomes 15 Years After Aortic Valve Replacement With the Freestyle Stentless Aortic Bioprosthesis" @default.
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• W1987478547 doi "https://doi.org/10.1016/j.athoracsur.2013.08.047" @default.
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