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- W1987486529 abstract "The electrochemical monitoring of DNA hybridization related to specific sequences on breast cancer 1 (BRCA1) DNA by using singlewalled carbon nanotube (SWCNT) based screen printed graphite electrodes (SPEs) was performed in this study. After the microscopic characterization of SWCNT-SPE, the optimization of assay was studied. The development of screen printing process combined with nanomaterial based disposable sensor technology with sensitivity, selectivity and reproducibility, has a great opportunity for DNA detection using differential pulse voltammetry (DPV) by measuring the guanine oxidation signal observed at +1.00 V in the presence of DNA hybridization between BRCA1 probe and its complementary target. The detection limit estimated for signal to noise ratio = 3 corresponds to 378.52 nM target concentration in the 40 μL samples. The voltammetric results on BRCA1 DNA hybridization were also complemented with electrochemical impedance spectroscopy (EIS)." @default.
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- W1987486529 date "2012-11-01" @default.
- W1987486529 modified "2023-10-16" @default.
- W1987486529 title "Electrochemical sensing of label free DNA hybridization related to breast cancer 1 gene at disposable sensor platforms modified with single walled carbon nanotubes" @default.
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- W1987486529 doi "https://doi.org/10.1016/j.electacta.2012.05.057" @default.
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