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• W1987489354 abstract "Abstract Herein, the enzymatic condensation of side chain‐protected peptide fragments using subtilisin A in anhydrous organic solvents is described. A screening with dipeptide Cbz‐Val‐Xxx carboxamidomethyl esters with H‐Xxx‐Val‐NH 2 nucleophiles was performed, wherein Xxx stands for every (side chain‐protected) amino acid residue. Finally, it was demonstrated that it is feasible to enzymatically condense larger peptide fragments (up to the 10‐mer level) bearing multiple side chain‐protecting groups with very high conversion." @default.
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• W1987489354 date "2013-01-04" @default.
• W1987489354 modified "2023-10-01" @default.
• W1987489354 title "Enzymatic Fragment Condensation of Side Chain-Protected Peptides using Subtilisin A in Anhydrous Organic Solvents: A General Strategy for Industrial Peptide Synthesis" @default.
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• W1987489354 doi "https://doi.org/10.1002/adsc.201200694" @default.
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