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• W1987606325 abstract "We investigated the continuing effects of exposure to ethynylestradiol (EE(2)) in juvenile grey mullet after transfer to a clean environment. Eleven-month-old juvenile fish containing immature phenotype gonad were fed dry diets; the low and high EE(2)-treated groups were fed diets with 0.04 and 4 μg EE(2)/g body weight for 4 weeks, respectively. After treatment, they were transferred to clean seawater, and reared with an EE(2) free diet for 350 days. Vitellogenin (VTG) was not detected in the serum of the control group throughout the experimental period. However, in both treatment groups, abnormal values of serum VTG were detected until approximately 100 days after transfer to a clean environment. In the control group, sex differentiation was not confirmed until 206 days after transfer to a clean environment. However, some of the fish in the 0.04 μg EE(2)-treated group had ovarian cavity and oocytes at 26 days. In most of the fish in the 4 μg EE(2)-treated group, the ovarian cavity had already appeared at the end of EE(2) treatment (0 day), and oocytes were observed at 26 days, suggesting that EE(2) accelerates ovarian differentiation. These results suggest that previous exposure to EE(2) has long-term effects on VTG synthesis and gonadal development." @default.
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• W1987606325 date "2011-11-01" @default.
• W1987606325 modified "2023-10-18" @default.
• W1987606325 title "Effects of ethynylestradiol on vitellogenin synthesis and sex differentiation in juvenile grey mullet (Mugil cephalus) persist after long-term exposure to a clean environment" @default.
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• W1987606325 doi "https://doi.org/10.1016/j.cbpc.2011.07.001" @default.
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