FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987621836> ?p ?o ?g. }

• W1987621836 endingPage "1503" @default.
• W1987621836 startingPage "1495" @default.
• W1987621836 abstract "Background: Type 2 diabetes is a chronic, progressive disease with a multi-faceted pathophysiology. Beyond the known defects of insulin resistance and β-cell insufficiency, derangement of incretin hormones normally produced from the gut wall in response to food intake play an important role. In recent years, the ‘incretin-based’ therapies (IBTs) have been developed to address hyperglycemia through either mimicking the action of the endogenous incretin glucagon-like polypeptide (GLP-1) (GLP-1 receptor agonists) or by inhibiting the activity of the enzyme that degrades GLP-1 (the dipeptyl peptidase-4 inhibitors). Objective: We reviewed available evidence on the glucose lowering and anti-atherogenic effects of IBT. Results: In addition to their glucose-lowering and weight-neutral or weight-reducing actions, IBT decrease systolic blood pressure and improve fasting and postprandial lipid parameters by reducing total-cholesterol, low-density lipoprotein-cholesterol and triglycerides concentrations, and increasing high-density lipoprotein-cholesterol values. Reduced high-sensitivity C-reactive protein levels and improved endothelial dysfunction have been reported too. Conclusions: IBT have several beneficial effects on cardiovascular risk factors and, for this reason, it has been recently suggested to extend the use of these drugs in diabetic patients with cardiovascular complications. Yet, the long-term effects of IBT on subclinical or clinical atherosclerosis remain to be established by future studies." @default.
• W1987621836 created "2016-06-24" @default.
• W1987621836 creator A5003833247 @default.
• W1987621836 creator A5008776901 @default.
• W1987621836 creator A5035698309 @default.
• W1987621836 creator A5049796469 @default.
• W1987621836 creator A5076416009 @default.
• W1987621836 date "2009-09-17" @default.
• W1987621836 modified "2023-09-23" @default.
• W1987621836 title "Glucose lowering and anti-atherogenic effects of incretin-based therapies: GLP-1 analogues and DPP-4-inhibitors" @default.
• W1987621836 cites W1585447752 @default.
• W1987621836 cites W1977119153 @default.
• W1987621836 cites W1984740259 @default.
• W1987621836 cites W1986085856 @default.
• W1987621836 cites W1989976483 @default.
• W1987621836 cites W2012506661 @default.
• W1987621836 cites W2018192866 @default.
• W1987621836 cites W2031891480 @default.
• W1987621836 cites W2032322539 @default.
• W1987621836 cites W2035474792 @default.
• W1987621836 cites W2045923887 @default.
• W1987621836 cites W2046613509 @default.
• W1987621836 cites W2047353065 @default.
• W1987621836 cites W2050826565 @default.
• W1987621836 cites W2061729221 @default.
• W1987621836 cites W2062883844 @default.
• W1987621836 cites W2071835038 @default.
• W1987621836 cites W2073099528 @default.
• W1987621836 cites W2085862152 @default.
• W1987621836 cites W2093738306 @default.
• W1987621836 cites W2096857379 @default.
• W1987621836 cites W2098459806 @default.
• W1987621836 cites W2103525547 @default.
• W1987621836 cites W2116697145 @default.
• W1987621836 cites W2126520659 @default.
• W1987621836 cites W2127409471 @default.
• W1987621836 cites W2129377335 @default.
• W1987621836 cites W2129730863 @default.
• W1987621836 cites W2129903164 @default.
• W1987621836 cites W2134361196 @default.
• W1987621836 cites W2143954917 @default.
• W1987621836 cites W2145335273 @default.
• W1987621836 cites W2149762820 @default.
• W1987621836 cites W2152978153 @default.
• W1987621836 cites W2162934281 @default.
• W1987621836 cites W2164416879 @default.
• W1987621836 cites W2166494634 @default.
• W1987621836 cites W2171512247 @default.
• W1987621836 cites W2325442204 @default.
• W1987621836 doi "https://doi.org/10.1517/14728220903241633" @default.
• W1987621836 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19758106" @default.
• W1987621836 hasPublicationYear "2009" @default.
• W1987621836 type Work @default.
• W1987621836 sameAs 1987621836 @default.
• W1987621836 citedByCount "76" @default.
• W1987621836 countsByYear W19876218362012 @default.
• W1987621836 countsByYear W19876218362013 @default.
• W1987621836 countsByYear W19876218362014 @default.
• W1987621836 countsByYear W19876218362015 @default.
• W1987621836 countsByYear W19876218362016 @default.
• W1987621836 countsByYear W19876218362017 @default.
• W1987621836 countsByYear W19876218362018 @default.
• W1987621836 countsByYear W19876218362019 @default.
• W1987621836 countsByYear W19876218362020 @default.
• W1987621836 countsByYear W19876218362021 @default.
• W1987621836 countsByYear W19876218362022 @default.
• W1987621836 countsByYear W19876218362023 @default.
• W1987621836 crossrefType "journal-article" @default.
• W1987621836 hasAuthorship W1987621836A5003833247 @default.
• W1987621836 hasAuthorship W1987621836A5008776901 @default.
• W1987621836 hasAuthorship W1987621836A5035698309 @default.
• W1987621836 hasAuthorship W1987621836A5049796469 @default.
• W1987621836 hasAuthorship W1987621836A5076416009 @default.
• W1987621836 hasBestOaLocation W19876218362 @default.
• W1987621836 hasConcept C126322002 @default.
• W1987621836 hasConcept C134018914 @default.
• W1987621836 hasConcept C156490143 @default.
• W1987621836 hasConcept C2776398474 @default.
• W1987621836 hasConcept C2777180221 @default.
• W1987621836 hasConcept C2777391703 @default.
• W1987621836 hasConcept C2778163477 @default.
• W1987621836 hasConcept C2778199505 @default.
• W1987621836 hasConcept C2778881409 @default.
• W1987621836 hasConcept C2780072125 @default.
• W1987621836 hasConcept C555293320 @default.
• W1987621836 hasConcept C71924100 @default.
• W1987621836 hasConceptScore W1987621836C126322002 @default.
• W1987621836 hasConceptScore W1987621836C134018914 @default.
• W1987621836 hasConceptScore W1987621836C156490143 @default.
• W1987621836 hasConceptScore W1987621836C2776398474 @default.
• W1987621836 hasConceptScore W1987621836C2777180221 @default.
• W1987621836 hasConceptScore W1987621836C2777391703 @default.
• W1987621836 hasConceptScore W1987621836C2778163477 @default.
• W1987621836 hasConceptScore W1987621836C2778199505 @default.
• W1987621836 hasConceptScore W1987621836C2778881409 @default.
• W1987621836 hasConceptScore W1987621836C2780072125 @default.
• W1987621836 hasConceptScore W1987621836C555293320 @default.
• W1987621836 hasConceptScore W1987621836C71924100 @default.

• next