FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987659576> ?p ?o ?g. }

• W1987659576 endingPage "572" @default.
• W1987659576 startingPage "565" @default.
• W1987659576 abstract "We performed a double-blind, placebo-controlled study to evaluate the efficacy of low and high dose of intravenous immunoglobulins (IVIG) in relapsing/remitting (RR) multiple sclerosis (MS). Patients (n = 49) with clinical definite RR MS were randomly allocated to three groups and treated with 0.2 g/kg (n = 17) or 0.4 g/kg (n = 15) once a month of IVIG and placebo (n = 17) for 12 months. Clinical data were assessed monthly and magnetic resonance imaging (MRI) was performed every 3 months during the study period. Annual relapse rate (ARR) and change of the mean Expanded Disability Status Scale (EDSS) and Neurological Rating Scale Score (NRSS) from baseline to study conclusion were used as the clinical end-points. For MRI activity total lesion volume on T2-weighted image (T2WI), new lesions and gadolinium (Gd)-enhanced lesions on T1WI were analysed. ARR in both IVIG groups (0.88 for 0.2 g/kg and 0.86 for 0.4 g/kg) was reduced compared with placebo (1.24) during treatment period. Neurological disability measured with EDSS decreased slightly in both the IVIG groups (0.029 and 0.066, respectively) and increased by 0.29 in placebo (P = 0.0117). The neurologic impairment measured by NRSS showed similar trend. The total lesion volume on T2WI increased by 13.56% in placebo whereas in the 0.4 g/kg IVIG group decreased by -3.95% and in the 0.2 g/kg IVIG group increased by 3.6%. The cumulative numbers of Gd-enhancing lesions and new T2WI lesions in the IVIG groups were reduced in comparison with the placebo group. Our findings suggest that the dose 0.2 g/kg of IVIG is equally effective as 0.4 g/kg in reducing MS activity." @default.
• W1987659576 created "2016-06-24" @default.
• W1987659576 creator A5020016996 @default.
• W1987659576 creator A5020533046 @default.
• W1987659576 creator A5074783682 @default.
• W1987659576 date "2002-11-01" @default.
• W1987659576 modified "2023-10-16" @default.
• W1987659576 title "No difference in efficacy of two different doses of intravenous immunoglobulins in MS: clinical and MRI assessment" @default.
• W1987659576 cites W1964180982 @default.
• W1987659576 cites W1964185985 @default.
• W1987659576 cites W1966734628 @default.
• W1987659576 cites W1967530329 @default.
• W1987659576 cites W1968294325 @default.
• W1987659576 cites W1975515356 @default.
• W1987659576 cites W1977024475 @default.
• W1987659576 cites W1982787660 @default.
• W1987659576 cites W1987476542 @default.
• W1987659576 cites W1997444752 @default.
• W1987659576 cites W1997981339 @default.
• W1987659576 cites W2000454394 @default.
• W1987659576 cites W2001447887 @default.
• W1987659576 cites W2019237986 @default.
• W1987659576 cites W2030248496 @default.
• W1987659576 cites W2030784878 @default.
• W1987659576 cites W2036781293 @default.
• W1987659576 cites W2038715205 @default.
• W1987659576 cites W2057119898 @default.
• W1987659576 cites W2076368828 @default.
• W1987659576 cites W2088678446 @default.
• W1987659576 cites W2089514317 @default.
• W1987659576 cites W2093997579 @default.
• W1987659576 cites W2095788709 @default.
• W1987659576 cites W2100721517 @default.
• W1987659576 cites W2109134103 @default.
• W1987659576 cites W2119168009 @default.
• W1987659576 cites W2119762128 @default.
• W1987659576 cites W2124262271 @default.
• W1987659576 cites W2130355701 @default.
• W1987659576 cites W2136209358 @default.
• W1987659576 cites W2155953981 @default.
• W1987659576 cites W2315610003 @default.
• W1987659576 cites W2321043971 @default.
• W1987659576 cites W2767648819 @default.
• W1987659576 cites W4231768803 @default.
• W1987659576 cites W4244567798 @default.
• W1987659576 doi "https://doi.org/10.1046/j.1468-1331.2002.00500.x" @default.
• W1987659576 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12453070" @default.
• W1987659576 hasPublicationYear "2002" @default.
• W1987659576 type Work @default.
• W1987659576 sameAs 1987659576 @default.
• W1987659576 citedByCount "73" @default.
• W1987659576 countsByYear W19876595762012 @default.
• W1987659576 countsByYear W19876595762013 @default.
• W1987659576 countsByYear W19876595762014 @default.
• W1987659576 countsByYear W19876595762015 @default.
• W1987659576 countsByYear W19876595762016 @default.
• W1987659576 countsByYear W19876595762017 @default.
• W1987659576 countsByYear W19876595762018 @default.
• W1987659576 countsByYear W19876595762022 @default.
• W1987659576 crossrefType "journal-article" @default.
• W1987659576 hasAuthorship W1987659576A5020016996 @default.
• W1987659576 hasAuthorship W1987659576A5020533046 @default.
• W1987659576 hasAuthorship W1987659576A5074783682 @default.
• W1987659576 hasConcept C126322002 @default.
• W1987659576 hasConcept C126838900 @default.
• W1987659576 hasConcept C141071460 @default.
• W1987659576 hasConcept C142724271 @default.
• W1987659576 hasConcept C143409427 @default.
• W1987659576 hasConcept C203014093 @default.
• W1987659576 hasConcept C204787440 @default.
• W1987659576 hasConcept C27081682 @default.
• W1987659576 hasConcept C2780640218 @default.
• W1987659576 hasConcept C2780892749 @default.
• W1987659576 hasConcept C2781156865 @default.
• W1987659576 hasConcept C2989005 @default.
• W1987659576 hasConcept C42219234 @default.
• W1987659576 hasConcept C535046627 @default.
• W1987659576 hasConcept C71924100 @default.
• W1987659576 hasConcept C90924648 @default.
• W1987659576 hasConceptScore W1987659576C126322002 @default.
• W1987659576 hasConceptScore W1987659576C126838900 @default.
• W1987659576 hasConceptScore W1987659576C141071460 @default.
• W1987659576 hasConceptScore W1987659576C142724271 @default.
• W1987659576 hasConceptScore W1987659576C143409427 @default.
• W1987659576 hasConceptScore W1987659576C203014093 @default.
• W1987659576 hasConceptScore W1987659576C204787440 @default.
• W1987659576 hasConceptScore W1987659576C27081682 @default.
• W1987659576 hasConceptScore W1987659576C2780640218 @default.
• W1987659576 hasConceptScore W1987659576C2780892749 @default.
• W1987659576 hasConceptScore W1987659576C2781156865 @default.
• W1987659576 hasConceptScore W1987659576C2989005 @default.
• W1987659576 hasConceptScore W1987659576C42219234 @default.
• W1987659576 hasConceptScore W1987659576C535046627 @default.
• W1987659576 hasConceptScore W1987659576C71924100 @default.
• W1987659576 hasConceptScore W1987659576C90924648 @default.
• W1987659576 hasIssue "6" @default.
• W1987659576 hasLocation W19876595761 @default.
• W1987659576 hasLocation W19876595762 @default.

• next