FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987682718> ?p ?o ?g. }

• W1987682718 abstract "Prestin is the motor protein of the outer hair cells of the organ of Corti and a key factor in ensuring a high level of sensitivity of mammalian hearing. The factors that influence prestin expression are still largely unknown. We studied the effects of the application of retinoic acid, a ligand of a nuclear receptor, and of butyric acid, an inhibitor of histone deacetylase activity, on the expression of mRNA of prestin and Gata-3 in the organotypic culture of the organ of Corti of newborn rats using RT-PCR. Application of retinoic acid at concentrations of 1-50 μM results in a dose-dependent expression decrease after two days in culture. Treatment with sodium butyrate (0.5-2 mM) elevated the expression of prestin and Gata-3. Statistically significant correlations between Gata-3 and prestin mRNA levels were observed under all conditions. The data indicate that retinoid nuclear transcription factors, GATA-3 and histone acetylation/deacetylation processes may have a regulatory role to play in prestin expression." @default.
• W1987682718 created "2016-06-24" @default.
• W1987682718 creator A5009296947 @default.
• W1987682718 creator A5016169130 @default.
• W1987682718 creator A5031360367 @default.
• W1987682718 creator A5039651718 @default.
• W1987682718 creator A5043433931 @default.
• W1987682718 creator A5083790396 @default.
• W1987682718 date "2011-06-10" @default.
• W1987682718 modified "2023-10-01" @default.
• W1987682718 title "Effects of retinoic acid and butyric acid on the expression of prestin and gata-3 in organotypic cultures of the organ of corti of newborn rats" @default.
• W1987682718 cites W1519680742 @default.
• W1987682718 cites W1564211606 @default.
• W1987682718 cites W1919133853 @default.
• W1987682718 cites W1968360258 @default.
• W1987682718 cites W1969278390 @default.
• W1987682718 cites W1970855616 @default.
• W1987682718 cites W1975067995 @default.
• W1987682718 cites W1978893041 @default.
• W1987682718 cites W1981262066 @default.
• W1987682718 cites W1981603375 @default.
• W1987682718 cites W1984656772 @default.
• W1987682718 cites W1991272901 @default.
• W1987682718 cites W2002254203 @default.
• W1987682718 cites W2007727790 @default.
• W1987682718 cites W2008129789 @default.
• W1987682718 cites W2008744414 @default.
• W1987682718 cites W2015193920 @default.
• W1987682718 cites W2019801761 @default.
• W1987682718 cites W2019928465 @default.
• W1987682718 cites W2024679508 @default.
• W1987682718 cites W2026237709 @default.
• W1987682718 cites W2028948821 @default.
• W1987682718 cites W2034646869 @default.
• W1987682718 cites W2038717281 @default.
• W1987682718 cites W2043263086 @default.
• W1987682718 cites W2046292900 @default.
• W1987682718 cites W2051232171 @default.
• W1987682718 cites W2053441451 @default.
• W1987682718 cites W2055583443 @default.
• W1987682718 cites W2060275385 @default.
• W1987682718 cites W2066073064 @default.
• W1987682718 cites W2071421856 @default.
• W1987682718 cites W2075468711 @default.
• W1987682718 cites W2077171500 @default.
• W1987682718 cites W2080911219 @default.
• W1987682718 cites W2091262287 @default.
• W1987682718 cites W2093163471 @default.
• W1987682718 cites W2093780475 @default.
• W1987682718 cites W2094898751 @default.
• W1987682718 cites W2099249565 @default.
• W1987682718 cites W2101242242 @default.
• W1987682718 cites W2108244474 @default.
• W1987682718 cites W2114589490 @default.
• W1987682718 cites W2115504899 @default.
• W1987682718 cites W2117358667 @default.
• W1987682718 cites W2126158121 @default.
• W1987682718 cites W2138755913 @default.
• W1987682718 cites W2140937256 @default.
• W1987682718 cites W2141208300 @default.
• W1987682718 cites W2141478391 @default.
• W1987682718 cites W2146073537 @default.
• W1987682718 cites W2149446263 @default.
• W1987682718 cites W2153550523 @default.
• W1987682718 cites W2156614086 @default.
• W1987682718 cites W2165431561 @default.
• W1987682718 cites W2172184136 @default.
• W1987682718 cites W2221833316 @default.
• W1987682718 doi "https://doi.org/10.1002/dneu.20881" @default.
• W1987682718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21344672" @default.
• W1987682718 hasPublicationYear "2011" @default.
• W1987682718 type Work @default.
• W1987682718 sameAs 1987682718 @default.
• W1987682718 citedByCount "9" @default.
• W1987682718 countsByYear W19876827182013 @default.
• W1987682718 countsByYear W19876827182015 @default.
• W1987682718 countsByYear W19876827182016 @default.
• W1987682718 countsByYear W19876827182017 @default.
• W1987682718 countsByYear W19876827182018 @default.
• W1987682718 countsByYear W19876827182019 @default.
• W1987682718 crossrefType "journal-article" @default.
• W1987682718 hasAuthorship W1987682718A5009296947 @default.
• W1987682718 hasAuthorship W1987682718A5016169130 @default.
• W1987682718 hasAuthorship W1987682718A5031360367 @default.
• W1987682718 hasAuthorship W1987682718A5039651718 @default.
• W1987682718 hasAuthorship W1987682718A5043433931 @default.
• W1987682718 hasAuthorship W1987682718A5083790396 @default.
• W1987682718 hasConcept C104317684 @default.
• W1987682718 hasConcept C105702510 @default.
• W1987682718 hasConcept C161879069 @default.
• W1987682718 hasConcept C2776202225 @default.
• W1987682718 hasConcept C2778305200 @default.
• W1987682718 hasConcept C2778585322 @default.
• W1987682718 hasConcept C2780130748 @default.
• W1987682718 hasConcept C2780283210 @default.
• W1987682718 hasConcept C2780659331 @default.
• W1987682718 hasConcept C2780898785 @default.
• W1987682718 hasConcept C2781121885 @default.
• W1987682718 hasConcept C55493867 @default.
• W1987682718 hasConcept C62478195 @default.

• next