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- W1987687575 abstract "Abstract The relationship between genetically determined polymorphic oxidation and acetylation and susceptibility to neoplastic diseases has aroused much interest. The aim of our study was to evaluate whether women with breast cancer differ from healthy women in their ability to oxidize sparteine and acetylate sulfadimidine as model drugs. The results of our study revealed a predominance of the percentage of extensive metabolizers (EMs) of sparteine (97.8%) among 90 women with breast cancer in comparison to the percentage of EM (93.2%) in 74 healthy women. Among very extensive metabolizers of sparteine (VEM), with metabolic ratio (MR)" @default.
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- W1987687575 date "1997-02-01" @default.
- W1987687575 modified "2023-10-17" @default.
- W1987687575 title "Evaluation of genetically determined sparteine oxidation and sulfadimidine acetylation polymorphism in women with breast cancer" @default.
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- W1987687575 doi "https://doi.org/10.1016/s0960-9776(97)90541-5" @default.
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