Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987693654> ?p ?o ?g. }
- W1987693654 endingPage "375" @default.
- W1987693654 startingPage "370" @default.
- W1987693654 abstract "Rationale: Inflammation is associated with symptoms in many chronic illnesses; however, this link has not been established in pulmonary arterial hypertension.Objectives: The objective of this study was to investigate the association between inflammatory markers and quality of life–related symptoms in patients with pulmonary arterial hypertension. We hypothesized that higher circulating IL-6 and tumor necrosis factor-α levels would be associated with worse quality of life–related symptoms.Methods: We performed a secondary analysis using baseline and 3-month assessments of 62 subjects in a clinical trial of aspirin and simvastatin to determine the association between plasma IL-6 and tumor necrosis factor-α levels and the Medical Outcomes Study Short Form-36 subscales (pain, vitality, mental health).Measurements and Main Results: The mean age was 49.7 ± 13.4 years; 87% were female. Higher IL-6 levels were significantly associated with lower Medical Outcomes Study Short Form-36 subscale scores, indicating worse bodily pain, vitality, and mental health (all P < 0.01). Higher tumor necrosis factor-α levels were significantly associated with increased bodily pain, but better mental health scores.Conclusions: IL-6 and tumor necrosis factor-α levels are associated with certain quality of life domains in patients with pulmonary arterial hypertension.Clinical trial registered with www.clinicaltrials.gov (NCT00384865)." @default.
- W1987693654 created "2016-06-24" @default.
- W1987693654 creator A5006597573 @default.
- W1987693654 creator A5012476885 @default.
- W1987693654 creator A5017257299 @default.
- W1987693654 creator A5017354943 @default.
- W1987693654 creator A5033758604 @default.
- W1987693654 creator A5045085370 @default.
- W1987693654 creator A5048908501 @default.
- W1987693654 creator A5066472508 @default.
- W1987693654 creator A5066688315 @default.
- W1987693654 creator A5069966002 @default.
- W1987693654 creator A5075841527 @default.
- W1987693654 creator A5081580894 @default.
- W1987693654 creator A5088894324 @default.
- W1987693654 creator A5089492738 @default.
- W1987693654 date "2015-03-01" @default.
- W1987693654 modified "2023-10-15" @default.
- W1987693654 title "Interleukin-6 and Tumor Necrosis Factor-α Are Associated with Quality of Life–Related Symptoms in Pulmonary Arterial Hypertension" @default.
- W1987693654 cites W1589127394 @default.
- W1987693654 cites W1956582637 @default.
- W1987693654 cites W1967341354 @default.
- W1987693654 cites W1969722648 @default.
- W1987693654 cites W1986866782 @default.
- W1987693654 cites W1992265643 @default.
- W1987693654 cites W1998207473 @default.
- W1987693654 cites W2001240716 @default.
- W1987693654 cites W2001558060 @default.
- W1987693654 cites W2003005311 @default.
- W1987693654 cites W2004028194 @default.
- W1987693654 cites W2010803460 @default.
- W1987693654 cites W2016748877 @default.
- W1987693654 cites W2034137314 @default.
- W1987693654 cites W2034686068 @default.
- W1987693654 cites W2049514672 @default.
- W1987693654 cites W2052050098 @default.
- W1987693654 cites W2052211155 @default.
- W1987693654 cites W2059367168 @default.
- W1987693654 cites W2063105933 @default.
- W1987693654 cites W2067299054 @default.
- W1987693654 cites W2071390439 @default.
- W1987693654 cites W2074987305 @default.
- W1987693654 cites W2084665133 @default.
- W1987693654 cites W2088024398 @default.
- W1987693654 cites W2088849545 @default.
- W1987693654 cites W2092266379 @default.
- W1987693654 cites W2094232837 @default.
- W1987693654 cites W2097740790 @default.
- W1987693654 cites W2099609273 @default.
- W1987693654 cites W2101821254 @default.
- W1987693654 cites W2103588309 @default.
- W1987693654 cites W2110000680 @default.
- W1987693654 cites W2113750014 @default.
- W1987693654 cites W2116350908 @default.
- W1987693654 cites W2120063760 @default.
- W1987693654 cites W2120386620 @default.
- W1987693654 cites W2127994875 @default.
- W1987693654 cites W2131305170 @default.
- W1987693654 cites W2140758044 @default.
- W1987693654 cites W2140972687 @default.
- W1987693654 cites W2141215255 @default.
- W1987693654 cites W2143315463 @default.
- W1987693654 cites W2154332638 @default.
- W1987693654 cites W2157601642 @default.
- W1987693654 cites W2163437068 @default.
- W1987693654 cites W2170043830 @default.
- W1987693654 cites W2272584680 @default.
- W1987693654 cites W2332535725 @default.
- W1987693654 cites W4255691408 @default.
- W1987693654 doi "https://doi.org/10.1513/annalsats.201410-463oc" @default.
- W1987693654 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4418312" @default.
- W1987693654 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25615959" @default.
- W1987693654 hasPublicationYear "2015" @default.
- W1987693654 type Work @default.
- W1987693654 sameAs 1987693654 @default.
- W1987693654 citedByCount "28" @default.
- W1987693654 countsByYear W19876936542015 @default.
- W1987693654 countsByYear W19876936542016 @default.
- W1987693654 countsByYear W19876936542017 @default.
- W1987693654 countsByYear W19876936542018 @default.
- W1987693654 countsByYear W19876936542019 @default.
- W1987693654 countsByYear W19876936542020 @default.
- W1987693654 countsByYear W19876936542021 @default.
- W1987693654 countsByYear W19876936542022 @default.
- W1987693654 countsByYear W19876936542023 @default.
- W1987693654 crossrefType "journal-article" @default.
- W1987693654 hasAuthorship W1987693654A5006597573 @default.
- W1987693654 hasAuthorship W1987693654A5012476885 @default.
- W1987693654 hasAuthorship W1987693654A5017257299 @default.
- W1987693654 hasAuthorship W1987693654A5017354943 @default.
- W1987693654 hasAuthorship W1987693654A5033758604 @default.
- W1987693654 hasAuthorship W1987693654A5045085370 @default.
- W1987693654 hasAuthorship W1987693654A5048908501 @default.
- W1987693654 hasAuthorship W1987693654A5066472508 @default.
- W1987693654 hasAuthorship W1987693654A5066688315 @default.
- W1987693654 hasAuthorship W1987693654A5069966002 @default.
- W1987693654 hasAuthorship W1987693654A5075841527 @default.
- W1987693654 hasAuthorship W1987693654A5081580894 @default.