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- W1987698311 abstract "We demonstrate a microfluidic device capable of tracking the volume of individual cells by integrating an on-chip volume sensor with pressure-activated cell trapping capabilities. The device creates a dynamic trap by operating in feedback; a cell is periodically redirected back and forth through a microfluidic volume sensor (Coulter principle). Sieve valves are positioned on both ends of the sensing channel, creating a physical barrier which enables media to be quickly exchanged while keeping a cell firmly in place. The volume of individual Saccharomyces cerevisiae cells was tracked over entire growth cycles, and the ability to quickly exchange media was demonstrated." @default.
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- W1987698311 date "2014-01-01" @default.
- W1987698311 modified "2023-09-26" @default.
- W1987698311 title "Quantifying the volume of single cells continuously using a microfluidic pressure-driven trap with media exchange" @default.
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- W1987698311 doi "https://doi.org/10.1063/1.4867035" @default.
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