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- W1987707948 abstract "Topical tretinoin (retinoic acid) modifies fine wrinkles and certain other features of human skin damaged by exposure to the sun (photodamage), but histologic changes do not account for this improvement. In mice with photodamage induced by ultraviolet light, effacement of fine wrinkles by tretinoin is correlated with dermal collagen synthesis but not with histologic changes. We investigated whether collagen synthesis was reduced in photodamaged human skin and, if so, whether it could be restored by treatment with topical tretinoin." @default.
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- W1987707948 date "1993-08-19" @default.
- W1987707948 modified "2023-10-17" @default.
- W1987707948 title "Restoration of Collagen Formation in Photodamaged Human Skin by Tretinoin (Retinoic Acid)" @default.
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- W1987707948 doi "https://doi.org/10.1056/nejm199308193290803" @default.
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