Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987727013> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W1987727013 endingPage "52" @default.
- W1987727013 startingPage "47" @default.
- W1987727013 abstract "Phosphorothioate (PT) oligonucleotides are designed as specific agents for antisense therapy although they have been reported to exert non-specific immunomodulatory effects. To elucidate further their actions, the effect of PT deoxyguanosine oligomers (S-oligo(dG)) on in vitro cytokine production by mouse splenocytes was studied. S-oligo(dG)20 inhibited production of INFγ induced by Con A, E. coli DNA or the combination of PMA and calcium ionophore A23187. The diester analogue was inactive, and of PT homo-oligomers tested, S-oligo(dG)20 was the most active. PT compounds with as few as 5 dG residues could also block INFγ production. These results indicate that base composition and length, as well as the PT backbone, contribute to the inhibition of INFγ production and extend the range of immunomodulatory effects of PT compounds." @default.
- W1987727013 created "2016-06-24" @default.
- W1987727013 creator A5008439845 @default.
- W1987727013 creator A5015062757 @default.
- W1987727013 date "1995-02-01" @default.
- W1987727013 modified "2023-09-27" @default.
- W1987727013 title "In vitro inhibition of murine IFNγ production by phosphorothioate deoxyguanosine oligomers" @default.
- W1987727013 cites W1458660061 @default.
- W1987727013 cites W1491935939 @default.
- W1987727013 cites W1507081668 @default.
- W1987727013 cites W1634119082 @default.
- W1987727013 cites W1752221293 @default.
- W1987727013 cites W1783734615 @default.
- W1987727013 cites W1942668068 @default.
- W1987727013 cites W1955661374 @default.
- W1987727013 cites W1969818257 @default.
- W1987727013 cites W1984400882 @default.
- W1987727013 cites W1986616196 @default.
- W1987727013 cites W1986673525 @default.
- W1987727013 cites W1995118424 @default.
- W1987727013 cites W2012699815 @default.
- W1987727013 cites W2016057259 @default.
- W1987727013 cites W2055978224 @default.
- W1987727013 cites W2075942059 @default.
- W1987727013 cites W2098743337 @default.
- W1987727013 cites W2099361175 @default.
- W1987727013 cites W3026227968 @default.
- W1987727013 cites W4233540413 @default.
- W1987727013 doi "https://doi.org/10.1016/0162-3109(95)00043-s" @default.
- W1987727013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7768671" @default.
- W1987727013 hasPublicationYear "1995" @default.
- W1987727013 type Work @default.
- W1987727013 sameAs 1987727013 @default.
- W1987727013 citedByCount "63" @default.
- W1987727013 countsByYear W19877270132012 @default.
- W1987727013 countsByYear W19877270132013 @default.
- W1987727013 countsByYear W19877270132016 @default.
- W1987727013 crossrefType "journal-article" @default.
- W1987727013 hasAuthorship W1987727013A5008439845 @default.
- W1987727013 hasAuthorship W1987727013A5015062757 @default.
- W1987727013 hasConcept C129312508 @default.
- W1987727013 hasConcept C153911025 @default.
- W1987727013 hasConcept C185592680 @default.
- W1987727013 hasConcept C189976730 @default.
- W1987727013 hasConcept C202751555 @default.
- W1987727013 hasConcept C203014093 @default.
- W1987727013 hasConcept C2778690821 @default.
- W1987727013 hasConcept C2779014961 @default.
- W1987727013 hasConcept C2780441211 @default.
- W1987727013 hasConcept C41625074 @default.
- W1987727013 hasConcept C552990157 @default.
- W1987727013 hasConcept C55493867 @default.
- W1987727013 hasConcept C86803240 @default.
- W1987727013 hasConceptScore W1987727013C129312508 @default.
- W1987727013 hasConceptScore W1987727013C153911025 @default.
- W1987727013 hasConceptScore W1987727013C185592680 @default.
- W1987727013 hasConceptScore W1987727013C189976730 @default.
- W1987727013 hasConceptScore W1987727013C202751555 @default.
- W1987727013 hasConceptScore W1987727013C203014093 @default.
- W1987727013 hasConceptScore W1987727013C2778690821 @default.
- W1987727013 hasConceptScore W1987727013C2779014961 @default.
- W1987727013 hasConceptScore W1987727013C2780441211 @default.
- W1987727013 hasConceptScore W1987727013C41625074 @default.
- W1987727013 hasConceptScore W1987727013C552990157 @default.
- W1987727013 hasConceptScore W1987727013C55493867 @default.
- W1987727013 hasConceptScore W1987727013C86803240 @default.
- W1987727013 hasIssue "1" @default.
- W1987727013 hasLocation W19877270131 @default.
- W1987727013 hasLocation W19877270132 @default.
- W1987727013 hasOpenAccess W1987727013 @default.
- W1987727013 hasPrimaryLocation W19877270131 @default.
- W1987727013 hasRelatedWork W1978153502 @default.
- W1987727013 hasRelatedWork W1987727013 @default.
- W1987727013 hasRelatedWork W2035327223 @default.
- W1987727013 hasRelatedWork W2061078869 @default.
- W1987727013 hasRelatedWork W2067554955 @default.
- W1987727013 hasRelatedWork W2717843124 @default.
- W1987727013 hasRelatedWork W2806054925 @default.
- W1987727013 hasRelatedWork W2895321476 @default.
- W1987727013 hasRelatedWork W3035897387 @default.
- W1987727013 hasRelatedWork W4323653549 @default.
- W1987727013 hasVolume "29" @default.
- W1987727013 isParatext "false" @default.
- W1987727013 isRetracted "false" @default.
- W1987727013 magId "1987727013" @default.
- W1987727013 workType "article" @default.