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- W1987763978 abstract "Starting from lactone-amide 8, easily derived from l-glutamic acid, enantioselective syntheses of (S)-tetrahydrofuran 2-carboxamide derivative 2 and a protected (S)-3-hydroxypiperidin-2-one (3) are reported. The building block 3 was converted to (2S,3R)-3-hydroxypipecolamide (6) by a three-step procedure. A solvent altered H-bonding capacity leading to a highly chemoselective tosylation of the primary hydroxyl group in the presence of an α-hydroxy-carboxamide was observed." @default.
- W1987763978 created "2016-06-24" @default.
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- W1987763978 date "2006-07-01" @default.
- W1987763978 modified "2023-10-05" @default.
- W1987763978 title "Syntheses of enantio-enriched chiral building blocks from l-glutamic acid" @default.
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- W1987763978 doi "https://doi.org/10.1016/j.tet.2006.05.013" @default.
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