Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987777995> ?p ?o ?g. }
- W1987777995 endingPage "L755" @default.
- W1987777995 startingPage "L750" @default.
- W1987777995 abstract "Lactoferrin and lysozyme are important antimicrobial compounds of airway surface liquid, derived predominantly from serous cells of submucosal glands but also from surface epithelium. Here we compared release of these compounds from the following human cell cultures: primary cultures of tracheal epithelium (HTE), Calu-3 cells (a lung adenocarcinoma cell line frequently used as a model of serous gland cells), 16HBE14o- cells (an SV40 transformed line from airway surface epithelium), T84 cells (a colon carcinoma cell line), and human foreskin fibroblasts (HFF). For lysozyme, baseline secretory rates were in the order Calu-3 > 16HBE14o- > HTE T84 > HFF = 0; for lactoferrin, the only cell type showing measurable release was HTE; for mucus, HTE > Calu-3 > 16HBE14o- T84 > HFF = 0. A wide variety of neurohumoral agents and inflammatory stimuli was without effect on lactoferrin and lysozyme release from HTE or Calu-3 cells, although forskolin did stimulate secretion of water and lysozyme from Calu-3 cells. However, the concentration of lysozyme in the forskolin-induced secretions was much less than in airway gland secretions. Thus our data cast doubt on the utility of Calu-3 cells as a model of airway serous gland cells but do suggest that HTE could prove highly suitable for studies of mucin synthesis and release." @default.
- W1987777995 created "2016-06-24" @default.
- W1987777995 creator A5018726205 @default.
- W1987777995 creator A5026572261 @default.
- W1987777995 creator A5028701888 @default.
- W1987777995 date "2004-04-01" @default.
- W1987777995 modified "2023-10-14" @default.
- W1987777995 title "Secretion of lactoferrin and lysozyme by cultures of human airway epithelium" @default.
- W1987777995 cites W1572737202 @default.
- W1987777995 cites W1582077381 @default.
- W1987777995 cites W1859763432 @default.
- W1987777995 cites W1879202914 @default.
- W1987777995 cites W1900298576 @default.
- W1987777995 cites W1963479597 @default.
- W1987777995 cites W1973010352 @default.
- W1987777995 cites W1974456086 @default.
- W1987777995 cites W1985699069 @default.
- W1987777995 cites W2005285859 @default.
- W1987777995 cites W2005644246 @default.
- W1987777995 cites W2010032940 @default.
- W1987777995 cites W2036797577 @default.
- W1987777995 cites W2043903911 @default.
- W1987777995 cites W2045419222 @default.
- W1987777995 cites W2054516272 @default.
- W1987777995 cites W2056524170 @default.
- W1987777995 cites W2065032868 @default.
- W1987777995 cites W2065816770 @default.
- W1987777995 cites W2073151710 @default.
- W1987777995 cites W2078920860 @default.
- W1987777995 cites W2081096967 @default.
- W1987777995 cites W2081149569 @default.
- W1987777995 cites W2081505147 @default.
- W1987777995 cites W2087765037 @default.
- W1987777995 cites W2098348905 @default.
- W1987777995 cites W2102730957 @default.
- W1987777995 cites W2108875315 @default.
- W1987777995 cites W2119979965 @default.
- W1987777995 cites W2128968040 @default.
- W1987777995 cites W2129557473 @default.
- W1987777995 cites W2129707656 @default.
- W1987777995 cites W2132552463 @default.
- W1987777995 cites W2135556820 @default.
- W1987777995 cites W2145517314 @default.
- W1987777995 cites W2152092223 @default.
- W1987777995 cites W2173303531 @default.
- W1987777995 cites W2183687504 @default.
- W1987777995 cites W2186471073 @default.
- W1987777995 cites W2269095518 @default.
- W1987777995 cites W2275892949 @default.
- W1987777995 cites W2335805947 @default.
- W1987777995 cites W2396750528 @default.
- W1987777995 cites W2411837661 @default.
- W1987777995 cites W2415909160 @default.
- W1987777995 cites W2464651764 @default.
- W1987777995 doi "https://doi.org/10.1152/ajplung.00326.2003" @default.
- W1987777995 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15003937" @default.
- W1987777995 hasPublicationYear "2004" @default.
- W1987777995 type Work @default.
- W1987777995 sameAs 1987777995 @default.
- W1987777995 citedByCount "67" @default.
- W1987777995 countsByYear W19877779952012 @default.
- W1987777995 countsByYear W19877779952013 @default.
- W1987777995 countsByYear W19877779952014 @default.
- W1987777995 countsByYear W19877779952015 @default.
- W1987777995 countsByYear W19877779952016 @default.
- W1987777995 countsByYear W19877779952017 @default.
- W1987777995 countsByYear W19877779952018 @default.
- W1987777995 countsByYear W19877779952019 @default.
- W1987777995 countsByYear W19877779952020 @default.
- W1987777995 countsByYear W19877779952021 @default.
- W1987777995 countsByYear W19877779952022 @default.
- W1987777995 countsByYear W19877779952023 @default.
- W1987777995 crossrefType "journal-article" @default.
- W1987777995 hasAuthorship W1987777995A5018726205 @default.
- W1987777995 hasAuthorship W1987777995A5026572261 @default.
- W1987777995 hasAuthorship W1987777995A5028701888 @default.
- W1987777995 hasConcept C134018914 @default.
- W1987777995 hasConcept C150173356 @default.
- W1987777995 hasConcept C153911025 @default.
- W1987777995 hasConcept C179264091 @default.
- W1987777995 hasConcept C18903297 @default.
- W1987777995 hasConcept C2776385078 @default.
- W1987777995 hasConcept C2776966407 @default.
- W1987777995 hasConcept C2777312293 @default.
- W1987777995 hasConcept C2779170986 @default.
- W1987777995 hasConcept C2779276759 @default.
- W1987777995 hasConcept C2780161494 @default.
- W1987777995 hasConcept C49039625 @default.
- W1987777995 hasConcept C529295009 @default.
- W1987777995 hasConcept C54355233 @default.
- W1987777995 hasConcept C55493867 @default.
- W1987777995 hasConcept C81885089 @default.
- W1987777995 hasConcept C86803240 @default.
- W1987777995 hasConcept C87568996 @default.
- W1987777995 hasConcept C95444343 @default.
- W1987777995 hasConceptScore W1987777995C134018914 @default.
- W1987777995 hasConceptScore W1987777995C150173356 @default.
- W1987777995 hasConceptScore W1987777995C153911025 @default.