FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987804387> ?p ?o ?g. }

• W1987804387 endingPage "57" @default.
• W1987804387 startingPage "41" @default.
• W1987804387 abstract "Kefir has a long tradition in human nutrition due to its presupposed health promoting effects. To investigate the potential contribution of bioactive peptides to the physiological effects of kefir, comprehensive analysis of the peptide profile was performed by nano-ESI-LTQ-Orbitrap MS coupled to nano-ultrahigh-performance liquid chromatography. Thus, 257 peptides were identified, mainly released from β-casein, followed by αS1-, κ-, and αS2-casein. Most (236) peptides were uniquely detected in kefir, but not in raw milk indicating that the fermentation step does not only increase the proteolytic activity 1.7- to 2.4-fold compared to unfermented milk, but also alters the composition of the peptide fraction. The influence of the microflora was determined by analyzing kefir produced from traditional kefir grains or commercial starter culture. Kefir from starter culture featured 230 peptide sequences and showed a significantly, 1.4-fold higher proteolytic activity than kefir from kefir grains with 127 peptides. A match of 97 peptides in both varieties indicates the presence of a typical kefir peptide profile that is not influenced by the individual composition of the microflora. Sixteen of the newly identified peptides were previously described as bioactive, including angiotensin-converting enzyme (ACE)-inhibitory, antimicrobial, immunomodulating, opioid, mineral binding, antioxidant, and antithrombotic effects. The present study describes a comprehensive peptide profile of kefir comprising 257 sequences. The peptide list was used to identify 16 bioactive peptides with ACE-inhibitory, antioxidant, antithrombotic, mineral binding, antimicrobial, immunomodulating and opioid activity in kefir. Furthermore, it was shown that a majority of the kefir peptides were not endogenously present in the raw material milk, but were released from milk caseins by proteases of the microbiota and are therefore specific for the product. Consequently, the proteolytic activity and the composition of the peptide profile can be controlled by the applied microflora (grains or starter culture). On the other hand, a considerable portion of the peptide profile was identified to be typical for kefir in general and independent from production parameters. In summary, the generated kefir peptide profile helped to reveal its origin and to identify bioactive peptides in kefir, which may advance the understanding of health benefits of this food product. The results further indicate that subsets of the kefir peptide list can be used as markers to control food authenticity, for example, to distinguish different types of kefir." @default.
• W1987804387 created "2016-06-24" @default.
• W1987804387 creator A5001078059 @default.
• W1987804387 creator A5003323107 @default.
• W1987804387 creator A5019219890 @default.
• W1987804387 creator A5038336177 @default.
• W1987804387 creator A5062412414 @default.
• W1987804387 creator A5068682855 @default.
• W1987804387 date "2015-03-01" @default.
• W1987804387 modified "2023-10-14" @default.
• W1987804387 title "Peptide profiling of bovine kefir reveals 236 unique peptides released from caseins during its production by starter culture or kefir grains" @default.
• W1987804387 cites W1975630793 @default.
• W1987804387 cites W1977174192 @default.
• W1987804387 cites W1978645542 @default.
• W1987804387 cites W1980387803 @default.
• W1987804387 cites W1986656413 @default.
• W1987804387 cites W1987002424 @default.
• W1987804387 cites W1989787662 @default.
• W1987804387 cites W2006145762 @default.
• W1987804387 cites W2008652795 @default.
• W1987804387 cites W2013177992 @default.
• W1987804387 cites W2021155760 @default.
• W1987804387 cites W2027378235 @default.
• W1987804387 cites W2028857649 @default.
• W1987804387 cites W2029513748 @default.
• W1987804387 cites W2031168055 @default.
• W1987804387 cites W2031549557 @default.
• W1987804387 cites W2038125104 @default.
• W1987804387 cites W2048958129 @default.
• W1987804387 cites W2056774361 @default.
• W1987804387 cites W2068521408 @default.
• W1987804387 cites W2069159595 @default.
• W1987804387 cites W2070135311 @default.
• W1987804387 cites W2075819111 @default.
• W1987804387 cites W2082514901 @default.
• W1987804387 cites W2084631914 @default.
• W1987804387 cites W2086809466 @default.
• W1987804387 cites W2088415970 @default.
• W1987804387 cites W2096442009 @default.
• W1987804387 cites W2110329577 @default.
• W1987804387 cites W2113438275 @default.
• W1987804387 cites W2117071648 @default.
• W1987804387 cites W2123406771 @default.
• W1987804387 cites W2130448576 @default.
• W1987804387 cites W2155843228 @default.
• W1987804387 cites W2161393176 @default.
• W1987804387 cites W2165457361 @default.
• W1987804387 cites W2166688273 @default.
• W1987804387 cites W2167427416 @default.
• W1987804387 cites W2333003186 @default.
• W1987804387 cites W2333874529 @default.
• W1987804387 cites W2335706826 @default.
• W1987804387 cites W234015304 @default.
• W1987804387 cites W4239106639 @default.
• W1987804387 doi "https://doi.org/10.1016/j.jprot.2015.01.005" @default.
• W1987804387 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25613046" @default.
• W1987804387 hasPublicationYear "2015" @default.
• W1987804387 type Work @default.
• W1987804387 sameAs 1987804387 @default.
• W1987804387 citedByCount "122" @default.
• W1987804387 countsByYear W19878043872015 @default.
• W1987804387 countsByYear W19878043872016 @default.
• W1987804387 countsByYear W19878043872017 @default.
• W1987804387 countsByYear W19878043872018 @default.
• W1987804387 countsByYear W19878043872019 @default.
• W1987804387 countsByYear W19878043872020 @default.
• W1987804387 countsByYear W19878043872021 @default.
• W1987804387 countsByYear W19878043872022 @default.
• W1987804387 countsByYear W19878043872023 @default.
• W1987804387 crossrefType "journal-article" @default.
• W1987804387 hasAuthorship W1987804387A5001078059 @default.
• W1987804387 hasAuthorship W1987804387A5003323107 @default.
• W1987804387 hasAuthorship W1987804387A5019219890 @default.
• W1987804387 hasAuthorship W1987804387A5038336177 @default.
• W1987804387 hasAuthorship W1987804387A5062412414 @default.
• W1987804387 hasAuthorship W1987804387A5068682855 @default.
• W1987804387 hasConcept C181199279 @default.
• W1987804387 hasConcept C185592680 @default.
• W1987804387 hasConcept C2775920511 @default.
• W1987804387 hasConcept C2776142715 @default.
• W1987804387 hasConcept C2777176278 @default.
• W1987804387 hasConcept C2778004101 @default.
• W1987804387 hasConcept C2778072784 @default.
• W1987804387 hasConcept C2779281246 @default.
• W1987804387 hasConcept C2781307694 @default.
• W1987804387 hasConcept C31903555 @default.
• W1987804387 hasConcept C523546767 @default.
• W1987804387 hasConcept C54355233 @default.
• W1987804387 hasConcept C55493867 @default.
• W1987804387 hasConcept C86803240 @default.
• W1987804387 hasConceptScore W1987804387C181199279 @default.
• W1987804387 hasConceptScore W1987804387C185592680 @default.
• W1987804387 hasConceptScore W1987804387C2775920511 @default.
• W1987804387 hasConceptScore W1987804387C2776142715 @default.
• W1987804387 hasConceptScore W1987804387C2777176278 @default.
• W1987804387 hasConceptScore W1987804387C2778004101 @default.
• W1987804387 hasConceptScore W1987804387C2778072784 @default.
• W1987804387 hasConceptScore W1987804387C2779281246 @default.

• next