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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987862498> ?p ?o ?g. }

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• W1987862498 abstract "The mouse alpha-fetoprotein (AFP) gene provides an excellent model system to study developmental gene activation and different aspects of liver-specific transcriptional control. AFP is activated early in hepatogenesis, repressed post-natally, and can be reactivated during liver regeneration and in hepatocellular carcinomas. Transgenic studies have also revealed that AFP enhancers, when linked individually to a heterologous promoter, can confer zonal control in the adult liver. Continued transgenic studies, combined with analysis using in vitro and tissue culture systems, will help elucidate mechanisms of transcriptional regulation during liver development and hepatocarcinogenesis." @default.
• W1987862498 created "2016-06-24" @default.
• W1987862498 creator A5024339038 @default.
• W1987862498 date "1999-04-01" @default.
• W1987862498 modified "2023-09-26" @default.
• W1987862498 title "Alpha-fetoprotein gene regulation: lessons from transgenic mice" @default.
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• W1987862498 doi "https://doi.org/10.1006/scbi.1998.0087" @default.
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