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- W1987911298 abstract "Sex differences exist in brain function and behavior. However, the underlying molecular mechanisms are only beginning to emerge. Recent studies in rodents have revealed molecular mechanisms underlying sex differences in memory formation. It is becoming clear that sex differences are not simply reflective of differences in sex hormones, but also reflect distinctions in synaptic signaling mechanisms including the role of synaptic kinases. Furthermore, there are sex differences in the activation of transcription factors and gene transcription during memory formation. This review discusses emerging evidence in the field and how these findings are providing a first step towards a molecular understanding of how sex differences impact on memory formation both in health and disease. Sex differences exist in brain function and behavior. However, the underlying molecular mechanisms are only beginning to emerge. Recent studies in rodents have revealed molecular mechanisms underlying sex differences in memory formation. It is becoming clear that sex differences are not simply reflective of differences in sex hormones, but also reflect distinctions in synaptic signaling mechanisms including the role of synaptic kinases. Furthermore, there are sex differences in the activation of transcription factors and gene transcription during memory formation. This review discusses emerging evidence in the field and how these findings are providing a first step towards a molecular understanding of how sex differences impact on memory formation both in health and disease." @default.
- W1987911298 created "2016-06-24" @default.
- W1987911298 creator A5085793083 @default.
- W1987911298 creator A5086626216 @default.
- W1987911298 date "2010-06-01" @default.
- W1987911298 modified "2023-10-12" @default.
- W1987911298 title "Towards a molecular understanding of sex differences in memory formation" @default.
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- W1987911298 doi "https://doi.org/10.1016/j.tins.2010.03.001" @default.
- W1987911298 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20356635" @default.
- W1987911298 hasPublicationYear "2010" @default.
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