Matches in SemOpenAlex for { <https://semopenalex.org/work/W1987914894> ?p ?o ?g. }
- W1987914894 endingPage "743" @default.
- W1987914894 startingPage "733" @default.
- W1987914894 abstract "Rescue of arrested and collapsed replication forks is essential for maintenance of genomic integrity. One system for origin of replication-independent loading of the DnaB replicative helicase and subsequent replisome reassembly requires the structure-specific recognition factor PriA and the assembly factors PriB and DnaT. Here, we provide biochemical evidence for an alternate system for DnaB loading that requires only PriC. Furthermore, the choice of which system is utilized during restart is dictated by the nature of the structure of the stalled replication fork. PriA-dependent reactions are most robust on fork structures with no gaps in the leading strand, such as is found at the junction of a D loop, while the PriC-dependent system preferentially utilizes fork structures with large gaps in the leading strand. These observations suggest that the type of initial damage on the DNA template and how the inactivated fork is processed ultimately influence the choice of enzymatic restart pathway." @default.
- W1987914894 created "2016-06-24" @default.
- W1987914894 creator A5068066930 @default.
- W1987914894 creator A5072077767 @default.
- W1987914894 date "2005-03-01" @default.
- W1987914894 modified "2023-10-07" @default.
- W1987914894 title "The Disposition of Nascent Strands at Stalled Replication Forks Dictates the Pathway of Replisome Loading during Restart" @default.
- W1987914894 cites W1482501584 @default.
- W1987914894 cites W1485021232 @default.
- W1987914894 cites W1510329672 @default.
- W1987914894 cites W1512516275 @default.
- W1987914894 cites W1518056484 @default.
- W1987914894 cites W1532280716 @default.
- W1987914894 cites W1546216437 @default.
- W1987914894 cites W1558934363 @default.
- W1987914894 cites W1564119816 @default.
- W1987914894 cites W1570361288 @default.
- W1987914894 cites W1603916894 @default.
- W1987914894 cites W1964370576 @default.
- W1987914894 cites W1966244556 @default.
- W1987914894 cites W1973721031 @default.
- W1987914894 cites W1985188411 @default.
- W1987914894 cites W1985662030 @default.
- W1987914894 cites W1987314616 @default.
- W1987914894 cites W1989782036 @default.
- W1987914894 cites W1998772598 @default.
- W1987914894 cites W1999925341 @default.
- W1987914894 cites W2000581423 @default.
- W1987914894 cites W2001764918 @default.
- W1987914894 cites W2004932687 @default.
- W1987914894 cites W2005954755 @default.
- W1987914894 cites W2007146285 @default.
- W1987914894 cites W2011435761 @default.
- W1987914894 cites W2015598559 @default.
- W1987914894 cites W2015840719 @default.
- W1987914894 cites W2025475717 @default.
- W1987914894 cites W2027762453 @default.
- W1987914894 cites W2065976083 @default.
- W1987914894 cites W2069757035 @default.
- W1987914894 cites W2070059581 @default.
- W1987914894 cites W2070910548 @default.
- W1987914894 cites W2077652583 @default.
- W1987914894 cites W2083123225 @default.
- W1987914894 cites W2097766238 @default.
- W1987914894 cites W2107267319 @default.
- W1987914894 cites W2113506888 @default.
- W1987914894 cites W2114809602 @default.
- W1987914894 cites W2124145206 @default.
- W1987914894 cites W2130395296 @default.
- W1987914894 cites W2138309358 @default.
- W1987914894 cites W2138997827 @default.
- W1987914894 cites W2140220147 @default.
- W1987914894 cites W2149730508 @default.
- W1987914894 cites W2154208108 @default.
- W1987914894 cites W2155885923 @default.
- W1987914894 cites W2163659193 @default.
- W1987914894 cites W2163827697 @default.
- W1987914894 cites W32943588 @default.
- W1987914894 cites W4234434887 @default.
- W1987914894 doi "https://doi.org/10.1016/j.molcel.2005.01.019" @default.
- W1987914894 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15749022" @default.
- W1987914894 hasPublicationYear "2005" @default.
- W1987914894 type Work @default.
- W1987914894 sameAs 1987914894 @default.
- W1987914894 citedByCount "136" @default.
- W1987914894 countsByYear W19879148942012 @default.
- W1987914894 countsByYear W19879148942013 @default.
- W1987914894 countsByYear W19879148942014 @default.
- W1987914894 countsByYear W19879148942015 @default.
- W1987914894 countsByYear W19879148942016 @default.
- W1987914894 countsByYear W19879148942017 @default.
- W1987914894 countsByYear W19879148942018 @default.
- W1987914894 countsByYear W19879148942019 @default.
- W1987914894 countsByYear W19879148942020 @default.
- W1987914894 countsByYear W19879148942021 @default.
- W1987914894 countsByYear W19879148942022 @default.
- W1987914894 countsByYear W19879148942023 @default.
- W1987914894 crossrefType "journal-article" @default.
- W1987914894 hasAuthorship W1987914894A5068066930 @default.
- W1987914894 hasAuthorship W1987914894A5072077767 @default.
- W1987914894 hasBestOaLocation W19879148941 @default.
- W1987914894 hasConcept C104317684 @default.
- W1987914894 hasConcept C104690221 @default.
- W1987914894 hasConcept C111919701 @default.
- W1987914894 hasConcept C116107829 @default.
- W1987914894 hasConcept C12590798 @default.
- W1987914894 hasConcept C143065580 @default.
- W1987914894 hasConcept C149187182 @default.
- W1987914894 hasConcept C159047783 @default.
- W1987914894 hasConcept C161223559 @default.
- W1987914894 hasConcept C175248279 @default.
- W1987914894 hasConcept C2777120639 @default.
- W1987914894 hasConcept C40523978 @default.
- W1987914894 hasConcept C41008148 @default.
- W1987914894 hasConcept C54355233 @default.
- W1987914894 hasConcept C552990157 @default.
- W1987914894 hasConcept C67705224 @default.
- W1987914894 hasConcept C70721500 @default.